Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.71 |
| ▸ | HTR2A | P28223 | 11/20 | 0.71 |
| ▸ | HTR7 | P34969 | 4/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.71 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.71 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.71 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.71 |
| ▸ | DRD1 | P21728 | 2/20 | 0.71 |
| ▸ | DRD4 | P21917 | 2/20 | 0.71 |
| ▸ | DRD5 | P21918 | 2/20 | 0.71 |
| ▸ | HTR1D | P28221 | 2/20 | 0.71 |
| ▸ | HTR1B | P28222 | 2/20 | 0.71 |
| ▸ | HTR2C | P28335 | 2/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.71 |
| ▸ | HRH1 | P35367 | 2/20 | 0.71 |
| ▸ | DRD3 | P35462 | 2/20 | 0.71 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.71 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.71 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343354 | 1.00 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| Paliperidone Palmitate SCHEMBL1871384 | 1.00 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| Paliperidone Palmitate SCHEMBL12415674 | 1.00 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL4263975 | 1.00 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| Paliperidone Palmitate SCHEMBL18131955 | 1.00 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL24018542 | 1.00 | DRD2 (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| Hydrochloric Acid SCHEMBL9196896 | 0.99 | DRD2 (0.70) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL14378106 | 0.96 | DRD2 (0.66) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL24465197 | 0.96 | DRD2 (0.66) | DRD2HTR2AHTR7KCNH2ADRA2A | |
| SCHEMBL22633922 | 0.95 | HTR2A (0.71) | DRD2HTR2AHTR7KCNH2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089076-A2 | PROCESSES FOR THE PREPARATION AND PURIFICATION OF PALIPERIDONE PALMITATE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-07-16 | — | — | WO | claimed |
| US-20090209757-A1 | Processes for the preparation and purification of paliperidone palmitate | TEVA PHARMACEUTICALS USA, INC. | 2009-08-20 | — | — | US | disclosed |
| US-20090209757-A1 | Processes for the preparation and purification of paliperidone palmitate | TEVA PHARMACEUTICALS USA, INC. | 2009-08-20 | — | — | US | disclosed |
| WO-2009089076-A2 | PROCESSES FOR THE PREPARATION AND PURIFICATION OF PALIPERIDONE PALMITATE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209757-A1 | Processes for the preparation and purification of paliperidone palmitate | GLP1R, DPP4, ADCYAP1R1 | DRD2 651/4885HTR2A 374/4885HTR7 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.