SCHEMBL24465281

SCHEMBL24465281

COCCOc1ccc(OS(=O)(=O)NS(=O)(=O)C(F)(F)F)c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.40
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 2/20 0.39
MCL1 Q07820 1/20 0.37
KDM4E B2RXH2 4/20 0.37
HPGD P15428 2/20 0.37
SLC2A1 P11166 2/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.35
CNR1 P21554 1/20 0.35
EGFR P00533 3/20 0.34
RXFP1 Q9HBX9 1/20 0.33
PIN1 Q13526 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24612913 0.80 MEN1 (0.38) HPGDSLC2A1KMT2AMEN1
SCHEMBL24465367 0.75 ALDH1A1 (0.41) ALDH1A1MCL1HPGDKMT2AMEN1
Tetrahydrothiophene SCHEMBL4427003 0.75 HTT (0.38) HTTALDH1A1HSD17B10KDM4EHPGD
SCHEMBL24383564 0.74
SCHEMBL18195881 0.74 MCL1 (0.42) HTTALDH1A1HSD17B10MCL1KDM4E
SCHEMBL18561726 0.74 IDO1 (0.50) KDM4ECNR1TSHRMAPK1IDO1
SCHEMBL30004116 0.74 IDO1 (0.50) KDM4ECNR1TSHRMAPK1IDO1
SCHEMBL18195886 0.73 MCL1 (0.49) ALDH1A1MCL1KDM4EHPGDKMT2A
Trifluoromethanesulfonic Acid SCHEMBL31168318 0.71 HTT (0.35) HTTALDH1A1HSD17B10KDM4EHPGD
Trifluoromethanesulfonic Acid SCHEMBL646424 0.71 HTT (0.35) HTTALDH1A1HSD17B10KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006921-A2 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND REACTION COMPOSITE Shin-Etsu Chemical Co., Ltd. (JP) 2022-06-01 EP disclosed