SCHEMBL24465372

SCHEMBL24465372

O=S(=O)(Cc1ccc(OCC2CO2)c2ccccc12)NS(=O)(=O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
GLA P06280 1/20 0.39
SLC2A1 P11166 3/20 0.38
TDP1 Q9NUW8 1/20 0.35
PKM P14618 2/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MCL1 Q07820 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
VDR P11473 1/20 0.31
P2RX4 Q99571 1/20 0.31
BCHE P06276 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
GCGR P47871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24452799 0.94 ALDH1A1 (0.39) ALDH1A1GLASLC2A1TDP1PKM
SCHEMBL24465276 0.79 ALDH1A1 (0.37) ALDH1A1GLASLC2A1TDP1PKM
SCHEMBL24465367 0.79 ALDH1A1 (0.41) ALDH1A1GLATDP1PKMLMNA
SCHEMBL24452530 0.77 MCL1 (0.45) ALDH1A1GLASLC2A1TDP1PKM
SCHEMBL24452770 0.76 ALDH1A1 (0.52) ALDH1A1TDP1PKMLMNAGAA
SCHEMBL24452831 0.74 ALDH1A1 (0.55) ALDH1A1GLASLC2A1TDP1PKM
SCHEMBL29417583 0.74 ALDH1A1 (0.65) ALDH1A1GLATDP1PKMLMNA
SCHEMBL19859437 0.74 ALDH1A1 (0.65) ALDH1A1GLATDP1PKMLMNA
SCHEMBL1715947 0.74 ALDH1A1 (0.65) ALDH1A1GLATDP1PKMLMNA
SCHEMBL24465352 0.73 ALDH1A1 (0.51) ALDH1A1TDP1PKMLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006921-A2 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND REACTION COMPOSITE Shin-Etsu Chemical Co., Ltd. (JP) 2022-06-01 EP disclosed