Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 5/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19432430 | 0.79 | NPC1 (0.53) | MEN1NPC1RAB9AKMT2AAPP | |
| SCHEMBL30932262 | 0.77 | PABPC1 (0.47) | ERBB2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9700727 | 0.75 | PIK3CG (0.46) | ERBB2MEN1KMT2AKDM4E | |
| SCHEMBL19075884 | 0.75 | NQO2 (0.57) | ERBB2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30932231 | 0.75 | PIK3CG (0.46) | ERBB2MEN1KMT2AKDM4E | |
| SCHEMBL19084327 | 0.75 | ERBB2 (0.39) | ERBB2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30932254 | 0.75 | KDM4E (0.52) | ERBB2PARP1MEN1NPC1RAB9A | |
| SCHEMBL30932232 | 0.75 | NQO2 (0.57) | ERBB2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1667048 | 0.75 | APP (0.37) | PARP1MEN1NPC1KMT2AAPP | |
| SCHEMBL2035725 | 0.75 | APP (0.37) | PARP1MEN1NPC1KMT2AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250238-B1 | ANTIBODY DRUG CONJUGATES | SORRENTO THERAPEUTICS INC (US) | 2022-06-01 | — | — | EP | disclosed |