Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932231 | 1.00 | PIK3CG (0.46) | PIK3CGALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9740990 | 0.81 | MAPT (0.35) | PIK3CGALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9700960 | 0.81 | MAPT (0.35) | PIK3CGALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL5157381 | 0.79 | PIK3CG (0.58) | PIK3CGALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9700694 | 0.78 | MMP1 (0.45) | DYRK1AERBB2 | |
| SCHEMBL30932262 | 0.77 | PABPC1 (0.47) | ALDH1A1KDM4EMEN1KMT2APIK3R1 | |
| SCHEMBL24465461 | 0.75 | ERBB2 (0.39) | KDM4EMEN1KMT2AERBB2 | |
| SCHEMBL19075884 | 0.75 | NQO2 (0.57) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL19084327 | 0.75 | ERBB2 (0.39) | KDM4EMEN1KMT2AERBB2 | |
| SCHEMBL30932232 | 0.75 | NQO2 (0.57) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |