SCHEMBL24465892

SCHEMBL24465892

Nc1cc2cccc3c2c2c(cccc12)CC3

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.60
HPGD P15428 7/20 0.60
KDM4E B2RXH2 6/20 0.60
LMNA P02545 3/20 0.60
GAA P10253 3/20 0.60
KMT2A Q03164 3/20 0.60
MEN1 O00255 2/20 0.60
MAPT P10636 1/20 0.60
HSD17B10 Q99714 5/20 0.43
CYP3A4 P08684 4/20 0.43
TSHR P16473 3/20 0.43
KEAP1 Q14145 2/20 0.43
TDP1 Q9NUW8 2/20 0.39
HPRT1 P00492 1/20 0.37
ALOX15 P16050 1/20 0.36
POLB P06746 3/20 0.35
NPC1 O15118 1/20 0.35
GLA P06280 1/20 0.35
PTBP1 P26599 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9058600 0.81 ALDH1A1 (0.50) ALDH1A1HPGDKDM4ELMNAGAA
SCHEMBL4978820 0.75 ALDH1A1 (1.00) ALDH1A1HPGDKDM4ELMNAGAA
SCHEMBL1899794 0.75 CYP1A2 (0.57) ALDH1A1HPGDKDM4ELMNAGAA
SCHEMBL31298002 0.75 CYP1A2 (0.57) ALDH1A1HPGDKDM4ELMNAGAA
SCHEMBL16107775 0.74 ALDH1A1 (0.54) ALDH1A1HPGDKDM4ELMNAGAA
Hydrochloric Acid SCHEMBL4707562 0.74 ALDH1A1 (0.96) ALDH1A1HPGDKDM4ELMNAGAA
Hydrochloric Acid SCHEMBL10601009 0.74 CYP1A2 (0.55) ALDH1A1HPGDKDM4ELMNAGAA
SCHEMBL16107888 0.74 ALDH1A1 (0.54) ALDH1A1HPGDKDM4ELMNAGAA
SCHEMBL5367551 0.72 ALDH1A1 (0.44) ALDH1A1HPGDKDM4ELMNAGAA
SCHEMBL154911 0.71 TSHR (0.70) ALDH1A1HPGDKDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3799144-B1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2022-06-01 EP disclosed