SCHEMBL5367551

SCHEMBL5367551

Nc1cc2c3c(cccc3c1)CC2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
MAPT P10636 4/20 0.44
LMNA P02545 3/20 0.44
KDM4E B2RXH2 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
HPGD P15428 3/20 0.44
GAA P10253 2/20 0.44
MPO P05164 1/20 0.40
HSD17B10 Q99714 5/20 0.39
CYP3A4 P08684 5/20 0.37
TSHR P16473 2/20 0.37
CASP1 P29466 3/20 0.35
CASP7 P55210 2/20 0.35
ALOX15 P16050 1/20 0.35
HBB P68871 1/20 0.35
HIF1A Q16665 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RAB9A P51151 2/20 0.34
PLAU P00749 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9471645 0.82 CASP1 (0.37) ALDH1A1HSD17B10TSHRCASP1CASP7
SCHEMBL30067264 0.78 MPO (0.47) ALDH1A1MAPTLMNAKDM4EMEN1
Acenaphthene SCHEMBL1162573 0.77 TSHR (0.57) ALDH1A1MAPTLMNAKDM4EMEN1
Acenaphthene SCHEMBL9017 0.77 TSHR (0.57) ALDH1A1MAPTLMNAKDM4EMEN1
Acenaphthene SCHEMBL598252 0.77 TSHR (0.57) ALDH1A1MAPTLMNAKDM4EMEN1
Acenaphthene SCHEMBL29386207 0.77 TSHR (0.57) ALDH1A1MAPTLMNAKDM4EMEN1
Acenaphthene SCHEMBL28028969 0.77 TSHR (0.57) ALDH1A1MAPTLMNAKDM4EMEN1
Acenaphthene SCHEMBL3416108 0.77 TSHR (0.57) ALDH1A1MAPTLMNAKDM4EMEN1
SCHEMBL5371245 0.75 LMNA (0.39) ALDH1A1MAPTLMNAKDM4EMEN1
SCHEMBL10424234 0.75 LMNA (0.39) ALDH1A1MAPTLMNAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1878774-A Preparation method of cucurbituril NEWSOUTH INNOVATIONS PTY LTD (AU) 2006-12-13 CN claimed
CN-109456807-A A kind of diesel fuel additives and its preparation method and application 广东交通职业技术学院 2019-03-12 CN disclosed
CN-107311888-B The manufacturing method of azo-compound 小西化学工业株式会社 2018-09-11 CN disclosed
CN-106748834-B A kind of method of 4,4- dimethoxys -2,2- bipyridyl silver catalytic hydrogenations aromatic nitro compound synthesis arylamine 陕西师范大学 2018-05-08 CN disclosed
CN-107311888-A The manufacture method of azo-compound 小西化学工业株式会社 2017-11-03 CN disclosed
CN-106748834-A A kind of method that the bipyridyl of 4,4 dimethoxy 2,2 silver catalytic hydrogenation aromatic nitro compound synthesizes arylamine 陕西师范大学 2017-05-31 CN disclosed
CN-106795335-A Pneumatic tire 住友橡胶工业株式会社 2017-05-31 CN disclosed
CN-101742913-A Baits for omnivores containing nitrite toxins INVASIVE ANIMALS CRC LTD 2010-06-16 CN disclosed
CN-100509761-C Labelling reagents, method for synthesis of said reagents and methods for detecting biological molecules BIO MERIEUX UNIVERSITY JOSEPH (FR) 2009-07-08 CN disclosed
CN-101421255-A Novel acetyl-coa carboxylase (acc) inhibitors and their use in diabetes, obesity and metabolic syndrome ABBOTT LAB (US) 2009-04-29 CN disclosed
CN-1081655-C Use of triazine-based UVAS for use as quenchers in paper-making processes CIBA SC HOLDING AG (CH) 2002-03-27 CN disclosed
CN-1253639-A Antireflective coating compositions for photoresist compositions and use thereof CLARIANT INT LTD (CH) 2000-05-17 CN disclosed
CN-1253638-A Light absorbing polymers CLARIANT INT LTD (CH) 2000-05-17 CN disclosed
CN-1242007-A Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising such compounds, and methods of inhibiting beta amyloid peptide release and/or its synthesis using such compounds ELAND PHARMACEUTICAL CORP (US) 2000-01-19 CN disclosed
CN-1221439-A Use of triazine-based UVAs as quenchers in papermaking processes CIBA GEIGY AG (CH) 1999-06-30 CN disclosed
CN-1207094-A Phenyl thiazole derivatives with anti herpes virus properties BOEHRINGER INGELHEIM PHARMA (US) 1999-02-03 CN disclosed
CN-1085556-A The 4-pyrimidyl and the pyridinyl derivatives of the indol-3-yl alkylpiperazine of anti-migraine BRISTOL MYERS SQUIBB CO (US) 1994-04-20 CN disclosed
CN-1032827-A Write or anti-medium and the correlation technique that duplicates of printing type face VICAT SA (FR) 1989-05-10 CN disclosed
CN-85109716-A Preparation octahydro indoles is (2,3-α) quinolizine-1-base-alkane hydroxy acid acid amides and acid salt thereof and the method that contains their pharmaceutical composition also 1986-10-08 CN disclosed
US-4174342-A N-(Acenaphthenyl)maleimides ABBOTT LABORATORIES (US) 1979-11-13 US disclosed