Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.39 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3491815 | 0.80 | EGFR (0.46) | EGFRMKNK1MKNK2EIF4EERBB2 | |
| SCHEMBL13402703 | 0.80 | MKNK2 (0.49) | EGFRMKNK1MKNK2EIF4EPDE4D | |
| SCHEMBL3794752 | 0.80 | MEN1 (0.47) | EGFRMKNK1MKNK2PDE4DPDE4A | |
| SCHEMBL13434887 | 0.79 | MKNK2 (0.45) | EGFRMKNK1MKNK2EIF4EERBB2 | |
| SCHEMBL13434868 | 0.79 | MKNK2 (0.42) | EGFRMKNK1MKNK2EIF4EPDE4D | |
| SCHEMBL3795402 | 0.78 | MKNK2 (0.48) | EGFRMKNK1MKNK2EIF4EPDE4D | |
| SCHEMBL3794206 | 0.78 | MKNK2 (0.56) | MKNK1MKNK2 | |
| SCHEMBL3805718 | 0.76 | EGFR (0.43) | EGFRMKNK1MKNK2EIF4EERBB2 | |
| SCHEMBL4593128 | 0.72 | ALDH1A1 (0.50) | EGFRMKNK1MKNK2PDE4DPDE4A | |
| SCHEMBL18839564 | 0.71 | MKNK2 (0.51) | EGFRMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006037-A1 | HETEROCYCLIC COMPOUND | Fimecs, Inc. (JP) | 2022-06-01 | — | — | EP | disclosed |