Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 14/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12339290 | 0.80 | GHSR (0.36) | GHSRCYP2D6MEN1ALDH1A1LMNA | |
| SCHEMBL13309419 | 0.79 | GHSR (0.36) | GHSRCYP2D6MEN1ALDH1A1LMNA | |
| SCHEMBL21165727 | 0.76 | GHSR (0.38) | GHSRCYP2D6MEN1ALDH1A1LMNA | |
| SCHEMBL12102102 | 0.76 | GHSR (0.38) | GHSRCYP2D6MEN1ALDH1A1LMNA | |
| SCHEMBL12339291 | 0.75 | SLC6A2 (0.41) | GHSRCYP2D6MEN1ALDH1A1LMNA | |
| SCHEMBL27010030 | 0.75 | GHSR (0.41) | GHSRCYP2D6MEN1ALDH1A1LMNA | |
| SCHEMBL27010028 | 0.75 | GHSR (0.41) | GHSRCYP2D6MEN1ALDH1A1LMNA | |
| SCHEMBL13309421 | 0.74 | SLC6A2 (0.40) | GHSRCYP2D6MEN1ALDH1A1LMNA | |
| SCHEMBL17914488 | 0.71 | ALOX5 (0.32) | — | |
| SCHEMBL12855097 | 0.71 | CYP2D6 (0.38) | GHSRCYP2D6MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |