SCHEMBL24467151

SCHEMBL24467151

CC(=O)c1ccc(C(=O)OF)o1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
KMT2A Q03164 5/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
ALDH1A1 P00352 3/20 0.41
HTT P42858 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 2/20 0.40
GLA P06280 2/20 0.40
MAPT P10636 1/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 3/20 0.35
KDM4E B2RXH2 2/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22845659 0.83 KMT2A (0.44) HDAC4HDAC6KMT2AMEN1CYP1A2
SCHEMBL54682 0.82 KMT2A (0.46) KMT2AMEN1CYP1A2CYP2C19ALDH1A1
SCHEMBL3140257 0.81 MEN1 (0.61) KMT2AMEN1CYP1A2CYP2C19ALDH1A1
SCHEMBL24467119 0.79 KMT2A (0.42) HDAC4HDAC6KMT2AMEN1CYP1A2
SCHEMBL23544342 0.78 KMT2A (0.41) HDAC4HDAC6KMT2AMEN1CYP1A2
SCHEMBL1828976 0.76 HDAC4 (0.65) HDAC4HDAC6KMT2AMEN1CYP1A2
SCHEMBL12140121 0.75 ALDH1A1 (0.54) KMT2AMEN1CYP1A2CYP2C19ALDH1A1
SCHEMBL17409146 0.73 KMT2A (0.41) HDAC4HDAC6KMT2AMEN1CYP1A2
SCHEMBL12400282 0.73 HDAC4 (0.45) HDAC4HDAC6KMT2AMEN1CYP1A2
SCHEMBL6239663 0.73 TDP1 (0.50) KMT2AMEN1ALDH1A1L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006078-A1 POLYMER COMPOUND COMPRISING BIOMASS-DERIVED CYCLIC MONOMER AND PREPARATION METHOD THEREFOR Kolon Industries, Inc. (KR) 2022-06-01 EP disclosed