Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239663 | 0.89 | TDP1 (0.50) | KMT2AALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL9375831 | 0.87 | ALDH1A1 (0.46) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL3063658 | 0.87 | KMT2A (0.38) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL14495734 | 0.87 | MAPT (0.41) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL12140121 | 0.86 | ALDH1A1 (0.54) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL22845659 | 0.85 | KMT2A (0.44) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL18403916 | 0.85 | KMT2A (0.41) | KMT2AALDH1A1KDM4EGLAGAA | |
| SCHEMBL528109 | 0.84 | — | — | |
| SCHEMBL183532 | 0.84 | — | — | |
| SCHEMBL10544541 | 0.83 | SMN1; SMN2 (0.43) | KMT2AALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362252-B | Method for preparing 2, 5-dimethyl furandicarboxylate from furan | 华东师范大学 | 2024-09-10 | — | — | CN | claimed |
| CN-117362252-A | Method for preparing 2, 5-dimethyl furandicarboxylate from furan | 华东师范大学 | 2024-01-09 | — | — | CN | claimed |
| EP-3231795-B1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | NINGBO INST MATERIALS TECH & ENG CAS (CN) | 2021-09-15 | — | — | EP | claimed |
| CN-112321545-A | Preparation method of 2, 5-diacetylfuran | 中国科学院宁波材料技术与工程研究所 | 2021-02-05 | — | — | CN | claimed |
| US-10125110-B2 | Method for preparing 2,5-disubstituted furan compound | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2018-11-13 | — | — | US | claimed |
| CN-105753821-B | A kind of preparation method of 2,5- furandicarboxylic acids | 中国科学院宁波材料技术与工程研究所 | 2018-11-02 | — | — | CN | claimed |
| US-20170320844-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2017-11-09 | — | — | US | claimed |
| EP-3231795-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | Ningbo Institute Of Material Technology And Engineering Chinese Academy of Sciences (CN) | 2017-10-18 | — | — | EP | claimed |
| CN-105753821-A | Preparation method of 2,5-furandicarboxylic acid | 中国科学院宁波材料技术与工程研究所 | 2016-07-13 | — | — | CN | claimed |
| CN-105732546-A | Preparation method of 2, 5-diacyl furan compound | 中国科学院宁波材料技术与工程研究所 | 2016-07-06 | — | — | CN | claimed |
| CN-105732545-A | Preparation method of 2, 5-diacyl furan compound | 中国科学院宁波材料技术与工程研究所 | 2016-07-06 | — | — | CN | claimed |
| CN-117362252-B | Method for preparing 2, 5-dimethyl furandicarboxylate from furan | 华东师范大学 | 2024-09-10 | — | — | CN | disclosed |
| CN-117362252-B | Method for preparing 2, 5-dimethyl furandicarboxylate from furan | 华东师范大学 | 2024-09-10 | — | — | CN | disclosed |
| CN-115850216-B | Stable isotope labeled 2, 5-furandicarboxylic acid-2-13Method for synthesizing COOH | 上海化工研究院有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117362252-A | Method for preparing 2, 5-dimethyl furandicarboxylate from furan | 华东师范大学 | 2024-01-09 | — | — | CN | disclosed |
| WO-2007071396-A2 | PYRAZINOYLGUANIDINE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY OR ALLERGIC CONDITIONS | NOVARTIS AG (CH) | 2007-06-28 | — | — | WO | disclosed |
| US-20060078351-A1 | Organophotoreceptors with a charge transport material having multiple vinyl-containing hydrazone groups | S-PRINTING SOLUTION CO., LTD. (KR) | 2006-04-13 | — | — | US | disclosed |
| EP-0804142-B1 | DIKETO COMPOUNDS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KGAA (DE) | 1999-03-17 | — | — | EP | disclosed |
| EP-0804142-A1 | DIKETO COMPOUNDS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022076-A1 | DIKETO COMPOUNDS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1996-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320844-A1 | METHOD FOR PREPARING 2,5-DISUBSTITUTED FURAN COMPOUND | ALOX5, PFAS, APEH | KMT2A 601/4885ALDH1A1 561/4885KDM4E 211/4885 |
| US-10125110-B2 | Method for preparing 2,5-disubstituted furan compound | ALOX5, PFAS, APEH | KMT2A 601/4885ALDH1A1 561/4885KDM4E 211/4885 |
| US-20060078351-A1 | Organophotoreceptors with a charge transport material having multiple vinyl-containing hydrazone groups | SLC16A7, SLC16A1, SLC16A3 | KMT2A 2663/4885ALDH1A1 695/4885KDM4E 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.