Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 13/20 | 0.66 |
| ▸ | BTK | Q06187 | 12/20 | 0.48 |
| ▸ | TXK | P42681 | 10/20 | 0.48 |
| ▸ | ITK | Q08881 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23365933 | 0.81 | JAK3 (1.00) | JAK3BTKTXKITK | |
| SCHEMBL20162010 | 0.80 | JAK3 (0.63) | JAK3BTKTXKITK | |
| SCHEMBL24467190 | 0.77 | BTK (0.71) | JAK3BTKTXKITK | |
| SCHEMBL24467251 | 0.75 | JAK3 (0.46) | JAK3BTKTXKITK | |
| SCHEMBL24467153 | 0.71 | JAK3 (0.48) | JAK3BTKTXKITK | |
| SCHEMBL24467287 | 0.69 | JAK3 (0.69) | JAK3BTKTXKITK | |
| SCHEMBL20162005 | 0.68 | JAK3 (0.39) | JAK3BTKTXKITK | |
| SCHEMBL24467248 | 0.68 | ITK (0.70) | JAK3BTKTXKITK | |
| SCHEMBL24467347 | 0.67 | JAK3 (0.68) | JAK3BTKTXKITK | |
| SCHEMBL24467232 | 0.65 | BTK (0.68) | JAK3BTKTXKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |