Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.79 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1437301 | 0.98 | TAAR1 (0.76) | TAAR1HTR2AADRA1AHTR2CMAPT | |
| SCHEMBL26065203 | 0.92 | TAAR1 (0.79) | TAAR1HTR2AADRA1AHTR2CCYP1A2 | |
| SCHEMBL1048621 | 0.88 | TAAR1 (1.00) | TAAR1HTR2AADRA1AHTR2C | |
| SCHEMBL29374207 | 0.88 | TAAR1 (1.00) | TAAR1HTR2AADRA1AHTR2C | |
| SCHEMBL18917027 | 0.82 | TAAR1 (0.62) | TAAR1HTR2AMAPTCYP1A2 | |
| SCHEMBL24960674 | 0.80 | TAAR1 (0.67) | TAAR1HTR2AADRA1AHTR2C | |
| SCHEMBL20969580 | 0.80 | TAAR1 (0.57) | TAAR1HTR2AADRA1AHTR2CCYP1A2 | |
| SCHEMBL24960680 | 0.80 | TAAR1 (0.67) | TAAR1HTR2AADRA1AHTR2C | |
| SCHEMBL19932825 | 0.80 | TAAR1 (0.52) | TAAR1MAPTSMN1; SMN2 | |
| SCHEMBL22381403 | 0.79 | TAAR1 (0.55) | TAAR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3483149-B1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | YUHAN CORP (KR) | 2021-01-13 | — | — | EP | disclosed |
| US-10383859-B2 | Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same | YUHAN CORPORATION (KR) | 2019-08-20 | — | — | US | disclosed |
| US-20190142809-A1 | Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same | YUHAN CORPORATION (KR) | 2019-05-16 | — | — | US | disclosed |
| EP-3483149-A1 | BENZO[D]THIAZOLE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Yuhan Corporation (KR) | 2019-05-15 | — | — | EP | disclosed |
| US-20180334436-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | VIIV HEALTHCARE UK LIMITED (GB) | 2018-11-22 | — | — | US | disclosed |
| EP-3383866-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | ViiV Healthcare UK Limited (GB) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017093938-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | VIIV HEALTHCARE UK LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |
| WO-2017093938-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | VIIV HEALTHCARE UK LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |
| US-8921382-B2 | Thiazolo[5,4-d] pyrimidines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8921382-B2 | Thiazolo[5,4-d] pyrimidines and their use as agrochemicals | DOW AGROSCIENCES, LLC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2011025505-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | DOW AGROSCIENCES LLC (US) | 2011-03-03 | — | — | WO | disclosed |
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| EP-1727789-A2 | PHENYLETHANOLAMINE DERIVATIVES AS BETA-2 AGONISTS | Pfizer Limited (GB) | 2006-12-06 | — | — | EP | disclosed |
| US-20050234097-A1 | Compounds useful for the treatment of diseases | PFIZER INC | 2005-10-20 | — | — | US | disclosed |
| WO-2005090287-A2 | PHENYLETHANOLAMINE DERIVATIVES AS BETA-2 AGONISTS | PFIZER LIMITED (GB) | 2005-09-29 | — | — | WO | disclosed |
| WO-2004071445-A2 | 2-(AMINOMETHYL)ARYLAMIDE ANALGESICS | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234097-A1 | Compounds useful for the treatment of diseases | LTC4S, CYP11B2, CYP11B1 | TAAR1 1799/4885HTR2A 3843/4885ADRA1A 635/4885 |
| US-20190142809-A1 | Benzo[D]Thiazole Derivative Or Salt Thereof, And Pharmaceutical Composition Including Same | ILK, SBDS, BDKRB1 | TAAR1 3745/4885HTR2A 4659/4885ADRA1A 3339/4885 |
| US-10383859-B2 | Benzo[d]thiazole derivative or salt thereof, and pharmaceutical composition including same | ILK, SBDS, BDKRB1 | TAAR1 3745/4885HTR2A 4659/4885ADRA1A 3339/4885 |
| US-20180334436-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | MAVS, EIF2AK2, SARS1 | TAAR1 3624/4885HTR2A 1685/4885ADRA1A 1919/4885 |
| US-20110054173-A1 | PTERIDINES AND THEIR USE AS AGROCHEMICALS | PIR, PFAS, PNPO | TAAR1 2305/4885HTR2A 1423/4885ADRA1A 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.