Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131044 | 0.68 | EPHX2 (0.58) | GRM5 | |
| SCHEMBL16980491 | 0.65 | PIK3CD (0.44) | MAPT | |
| SCHEMBL22893351 | 0.63 | MAPT (0.59) | HCRTR2MAPT | |
| SCHEMBL13145213 | 0.61 | GAA (0.44) | MAPT | |
| SCHEMBL15723656 | 0.61 | GAA (0.48) | MAPT | |
| SCHEMBL21099963 | 0.60 | MAPT (0.41) | MAPT | |
| SCHEMBL21696597 | 0.60 | GAA (0.47) | HCRTR2MAPT | |
| SCHEMBL27780282 | 0.59 | GRM5 (0.44) | GRM5 | |
| SCHEMBL13257065 | 0.59 | PIK3CD (0.58) | HCRTR2MAPT | |
| SCHEMBL15730093 | 0.58 | GAA (0.64) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4005569-A2 | COMPOSITIONS FOR TREATING AND/OR PREVENTING CELL OR TISSUE NECROSIS SPECIFICALLY TARGETING CATHEPSIN C AND/OR CELA1 AND/OR CELA3A AND/OR STRUCTURALLY RELATED ENZYMES THERETO | ELA Pharma Ltd (IL) | 2022-06-01 | — | — | EP | disclosed |