Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 16/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779443 | 0.86 | PRCP (0.38) | HTR2B | |
| SCHEMBL1293292 | 0.85 | HTR2B (0.42) | HTR2BADRA1A | |
| SCHEMBL24015824 | 0.85 | HTR2B (0.40) | HTR2BADRA1A | |
| SCHEMBL934063 | 0.85 | HTR2B (0.42) | HTR2BADRA1A | |
| SCHEMBL25591844 | 0.81 | RIPK1 (0.53) | HTR2BADRA1A | |
| SCHEMBL27758908 | 0.80 | PREP (0.38) | HTR2B | |
| SCHEMBL239739 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL47019 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL34474164 | 0.79 | ALDH1A1 (0.46) | — | |
| SCHEMBL27780329 | 0.79 | HTR2B (0.54) | GRM5HTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101558059-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-12-03 | — | — | CN | claimed |
| CN-101558059-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | CN | claimed |