Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CASP7 | P55210 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP5 | P51878 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29208842 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KDM4ETAAR1CASP1CYP1A2 | |
| SCHEMBL24467769 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4ETAAR1CASP1CYP1A2 | |
| SCHEMBL24968325 | 0.91 | ALDH1A1 (0.50) | ALDH1A1KDM4ETAAR1CASP1CYP1A2 | |
| SCHEMBL15000813 | 0.81 | POLB (0.47) | ALDH1A1KDM4ECYP1A2TSHRKMT2A | |
| SCHEMBL26157259 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4ETAAR1CASP1CYP1A2 | |
| SCHEMBL3668289 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4ETAAR1CASP1CYP1A2 | |
| SCHEMBL2365777 | 0.79 | DDB1 (0.49) | ALDH1A1KDM4ECYP1A2HSD17B10USP2 | |
| SCHEMBL24467776 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4ETAAR1CASP1CYP1A2 | |
| SCHEMBL1550925 | 0.78 | SLC6A9 (0.37) | KDM4ETSHRCYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL3670082 | 0.78 | ALDH1A1 (0.62) | ALDH1A1KDM4ETAAR1CASP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2023001247-A1 | PYRIDAZINONE COMPOUND | 南京明德新药研发有限公司 | 2023-01-26 | — | — | WO | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |