Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631771 | 1.00 | HRH4 (0.47) | HRH4HRH3PLD1DDB1CRBN | |
| SCHEMBL19203782 | 0.81 | HRH4 (0.37) | HRH4HRH3PLD1DDB1CRBN | |
| SCHEMBL24467748 | 0.79 | HRH4 (0.47) | HRH4HRH3SLC6A9HTR3A | |
| SCHEMBL2365777 | 0.75 | DDB1 (0.49) | HRH4HRH3PLD1DDB1CRBN | |
| SCHEMBL29631816 | 0.74 | SLC6A9 (0.44) | HRH3KDM4ESLC6A9 | |
| SCHEMBL2629281 | 0.74 | PLD1 (0.47) | HRH4HRH3PLD1ALDH1A1KDM4E | |
| SCHEMBL30899619 | 0.73 | NCF1 (0.41) | HRH4HRH3PIM1PIM3PIM2 | |
| SCHEMBL1763039 | 0.73 | PLD1 (0.46) | HRH4HRH3PLD1ALDH1A1KDM4E | |
| SCHEMBL25246367 | 0.73 | PLD1 (0.46) | HRH4HRH3PLD1ALDH1A1KDM4E | |
| SCHEMBL14916857 | 0.73 | HRH3 (0.50) | HRH4HRH3PLD1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157396-A | Pyridazinone derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |
| WO-2022111700-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF IN MEDICINE | 成都百裕制药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |