Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11889494 | 0.94 | AR (0.53) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL10656932 | 0.89 | AR (0.50) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL14962791 | 0.88 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL26113771 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL12515792 | 0.88 | AR (0.49) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL12516025 | 0.87 | AR (0.54) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL15723550 | 0.85 | SMN1; SMN2 (0.56) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL29944931 | 0.84 | SMN1; SMN2 (0.57) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL20892205 | 0.83 | THRB (0.58) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL14085624 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112943-A1 | POLYCARBONATE AND COMPOSITIONS AND ARTICLES COMPRISING THE POLYCARBONATE | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2022-06-02 | — | — | WO | disclosed |