Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656932 | 0.95 | AR (0.50) | ARKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL14962791 | 0.94 | KDM4E (0.50) | ARKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL26113771 | 0.94 | KDM4E (0.62) | ARKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL12515792 | 0.94 | AR (0.49) | ARKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL24468248 | 0.94 | KDM4E (0.53) | ARKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL12516025 | 0.92 | AR (0.54) | ARKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL29944931 | 0.90 | SMN1; SMN2 (0.57) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL20892205 | 0.89 | THRB (0.58) | ARKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL10030181 | 0.87 | L3MBTL1 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL14173142 | 0.84 | POLB (0.56) | ARKDM4EPOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154756-A2 | THIONOLACTONES AS ADDITIVES FOR VINYL NETWORK DEGRADATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-08-17 | — | — | WO | disclosed |
| EP-3643318-A1 | A BIOMIMETIC PEPTIDE AND BIODEGRADABLE DELIVERY PLATFORM FOR THE TREATMENT OF ANGIOGENESIS- AND LYMPHANGIOGENESIS-DEPENDENT DISEASES | The Johns Hopkins University (US) | 2020-04-29 | — | — | EP | disclosed |
| EP-3003343-B1 | A BIOMIMETIC PEPTIDE AND BIODEGRADABLE DELIVERY PLATFORM FOR THE TREATMENT OF ANGIOGENESIS- AND LYMPHANGIOGENESIS-DEPENDENT DISEASES | UNIV JOHNS HOPKINS (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-2670375-B1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2019-05-01 | — | — | EP | disclosed |
| EP-2670375-B1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2019-05-01 | — | — | EP | disclosed |
| WO-2019070727-A2 | NONVIRAL GENE TRANSFER TO THE SUPRACHOROIDAL SPACE | THE JOHNS HOPKINS UNIVERSITY (US) | 2019-04-11 | — | — | WO | disclosed |
| EP-3107523-B1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2018-10-17 | — | — | EP | disclosed |
| US-10004669-B2 | Dental composition and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-06-26 | — | — | US | disclosed |
| US-10004669-B2 | Dental composition and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-06-26 | — | — | US | disclosed |
| US-10004669-B2 | Dental composition and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-06-26 | — | — | US | disclosed |
| WO-2015126862-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-11-14 | — | — | US | disclosed |
| US-8431625-B2 | Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431625-B2 | Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| EP-2481390-A1 | Dental composition, method of producing and use thereof | 3M Innovative Properties Company (US) | 2012-08-01 | — | — | EP | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| EP-1942125-A1 | Compositions curable by ring opening metathesis polymerarization at low temperatures and their application in the dental field | 3M Innovative Properties Company (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008077001-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | PAM, PTMS, ACR | AR 577/4885KDM4E 132/4885POLB 525/4885 |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | DNMT3B, HMBS, MMAB | AR 2936/4885KDM4E 3465/4885POLB 65/4885 |
| US-10004669-B2 | Dental composition and use thereof | ACR, CAD, FHIT | AR 2518/4885KDM4E 425/4885POLB 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.