Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15306831 | 0.82 | KDM4E (0.41) | — | |
| SCHEMBL15339594 | 0.80 | — | — | |
| SCHEMBL3581100 | 0.77 | PARP1 (0.47) | — | |
| SCHEMBL24752129 | 0.76 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL18739049 | 0.69 | BUB1 (0.30) | BUB1 | |
| SCHEMBL3584083 | 0.69 | PRKCI (0.31) | BUB1 | |
| SCHEMBL16664933 | 0.69 | ADRA2A (0.31) | BUB1 | |
| SCHEMBL15308536 | 0.69 | CCR1 (0.35) | BUB1 | |
| SCHEMBL30507904 | 0.69 | PRKCI (0.31) | BUB1 | |
| SCHEMBL8482964 | 0.69 | AXL (0.31) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115301-A1 | MODIFIED ISOINDOLINONES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2022-06-02 | — | — | WO | disclosed |