Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3463711 | 0.78 | PRKCI (0.35) | HTR2AHTR2CPRKCIDRD2DRD3 | |
| SCHEMBL9089860 | 0.74 | ERN1 (0.39) | HTR2APRKCIERN1DRD2DRD3 | |
| SCHEMBL26230377 | 0.73 | DRD2 (0.37) | PRKCIERN1DRD2DRD3NPC1 | |
| SCHEMBL15056861 | 0.73 | ERN1 (0.42) | HTR2APRKCIERN1DRD2DRD3 | |
| SCHEMBL24469473 | 0.73 | PRKCI (0.34) | PRKCIERN1DRD2DRD3NPC1 | |
| SCHEMBL984492 | 0.72 | PRKCI (0.48) | PRKCIERN1DRD2DRD3MAPT | |
| SCHEMBL24469648 | 0.70 | PDE2A (0.37) | HTR2AHTR2CHTR2BPRKCIERN1 | |
| SCHEMBL31540886 | 0.70 | PRKCI (0.47) | PRKCIERN1DRD2DRD3MAPT | |
| SCHEMBL31540883 | 0.70 | PRKCI (0.47) | PRKCIERN1DRD2DRD3MAPT | |
| SCHEMBL12410553 | 0.70 | HTR2A (0.37) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111498-A1 | PYRIMIDINEDIONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2022-06-02 | — | — | WO | disclosed |