SCHEMBL984492

SCHEMBL984492

c1c2c(cc3c1OCC3)OCC2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.48
DYRK1A Q13627 3/20 0.44
DRD2 P14416 4/20 0.43
DRD3 P35462 4/20 0.43
DYRK2 Q92630 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
ERN1 O75460 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31540886 0.91 PRKCI (0.47) PRKCIDYRK1ADRD2DRD3DYRK2
SCHEMBL31540883 0.91 PRKCI (0.47) PRKCIDYRK1ADRD2DRD3DYRK2
SCHEMBL7082445 0.87 DRD2 (0.45) PRKCIDYRK1ADRD2DRD3DYRK2
SCHEMBL15290407 0.87 DRD2 (0.45) PRKCIDYRK1ADRD2DRD3DYRK2
SCHEMBL10487287 0.85 DRD2 (0.44) PRKCIDYRK1ADRD2DRD3DYRK2
SCHEMBL12438576 0.82 DYRK1A (0.46) PRKCIDYRK1ADRD2DRD3DYRK2
SCHEMBL1701459 0.82 AHR (0.42) PRKCIDYRK1ADRD2DRD3DYRK2
SCHEMBL13100028 0.82 PKLR (0.43) PRKCIDYRK1ADRD2DRD3DYRK2
SCHEMBL9377723 0.80 PRKCI (0.37) PRKCIDYRK1ADRD2DRD3DYRK2
SCHEMBL2131895 0.78 PRKCI (0.36) PRKCIDYRK1ADRD2DRD3DYRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115651448-A Conductive ink with n-type conductivity and preparation and application thereof 华南理工大学 2023-01-31 CN claimed
US-20250223263-A1 SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME NodThera Limited (GB) 2025-07-10 US disclosed
US-12247011-B2 Selective inhibitors of NLRP3 inflammasome NodThera Limited (GB) 2025-03-11 US disclosed
CN-119230299-A Solid-state capacitor and preparation method thereof 聚镕光电(广州)新材料科技有限公司 2024-12-31 CN disclosed
CN-119108509-A Negative electrode plate, preparation method thereof and secondary battery 蜂巢能源科技股份有限公司 2024-12-10 CN disclosed
US-11845715-B2 2023-12-19 US disclosed
US-11845715-B2 2023-12-19 US disclosed
US-11840543-B2 Compounds and uses THE UNIVERSITY OF QUEENSLAND (AU) 2023-12-12 US disclosed
US-11840543-B2 Compounds and uses THE UNIVERSITY OF QUEENSLAND (AU) 2023-12-12 US disclosed
US-11829036-B2 Optically anisotropic multilayer product and method for producing same ZEON CORPORATION (JP) 2023-11-28 US disclosed
US-20100266507-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2010-10-21 US disclosed
US-20100266507-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2010-10-21 US disclosed
US-20100016401-A1 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES Actelion Phamaceuticals Ltd. (CH) 2010-01-21 US disclosed
US-7208512-B2 Benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma ALCON, INC. (CH) 2007-04-24 US disclosed
US-7208512-B2 Benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma ALCON, INC. (CH) 2007-04-24 US disclosed
US-7208512-B2 Benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma ALCON, INC. (CH) 2007-04-24 US disclosed
US-20060009503-A1 Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma NOVARTIS AG (CH) 2006-01-12 US disclosed
EP-1455780-A4 NOVEL BENZODIFURANIMIDAZOLINE AND BENZOFURANIMIDAZOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF GLAUCOMA ALCON INC (CH) 2005-04-06 EP disclosed
EP-1455780-A1 NOVEL BENZODIFURANIMIDAZOLINE AND BENZOFURANIMIDAZOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF GLAUCOMA Alcon, Inc. (CH) 2004-09-15 EP disclosed
WO-2003053436-A1 NOVEL BENZODIFURANIMIDAZOLINE AND BENZOFURANIMIDAZOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF GLAUCOMA ALCON, INC. (CH) 2003-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12247011-B2 Selective inhibitors of NLRP3 inflammasome NLRP3, NOD1, NLRP1 PRKCI 2063/4885DYRK1A 4802/4885DRD2 4867/4885
US-20100266507-A1 LUMINESCENT COMPOUNDS SQLE, COASY, ZKSCAN2 PRKCI 407/4885DYRK1A 2372/4885DRD2 4400/4885
US-20250223263-A1 SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME NLRP3, NOD1, NLRP1 PRKCI 2063/4885DYRK1A 4802/4885DRD2 4867/4885
US-11845715-B2 NLRP3, PYCARD, NOD1 PRKCI 2390/4885DYRK1A 4428/4885DRD2 4758/4885
US-20060009503-A1 Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma AIFM1, MFN2, SIRT1 PRKCI 2909/4885DYRK1A 3558/4885DRD2 2460/4885
US-11840543-B2 Compounds and uses NLRP3, NOD1, IAPP PRKCI 1575/4885DYRK1A 2843/4885DRD2 3770/4885
US-20100016401-A1 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES HCRTR1, HCRTR2, CNR1 PRKCI 4070/4885DYRK1A 3821/4885DRD2 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.