Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319262 | 0.83 | GAA (0.42) | CYP2C19PKMGAA | |
| SCHEMBL28310610 | 0.83 | KMT2A (0.43) | KMT2ACYP2C19STAT3ALDH1A1HPGD | |
| SCHEMBL143673 | 0.83 | KMT2A (0.39) | KMT2ACYP2C19STAT3ALDH1A1HPGD | |
| SCHEMBL3981081 | 0.83 | KMT2A (0.39) | KMT2ACYP2C19STAT3ALDH1A1HPGD | |
| SCHEMBL82964 | 0.81 | GAA (0.42) | CYP2C19ALDH1A1PKMGAA | |
| SCHEMBL3479164 | 0.80 | STAT3 (0.40) | KMT2ACYP2C19STAT3ALDH1A1HPGD | |
| SCHEMBL28310624 | 0.77 | KMT2A (0.43) | KMT2ACYP2C19STAT3ALDH1A1HSD11B1 | |
| SCHEMBL2446969 | 0.76 | KMT2A (0.41) | KMT2AALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL16538612 | 0.75 | PSMD10 (0.39) | KMT2ACYP2C19STAT3ALDH1A1HPGD | |
| SCHEMBL16538626 | 0.75 | PSMD10 (0.39) | KMT2ACYP2C19STAT3ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722727-B2 | Antifungal agents | Seynix, Inc. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20110224228-A1 | ANTIFUNGAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224228-A1 | ANTIFUNGAL AGENTS | GMDS, GBA3, UGGT1 | KMT2A 4698/4885CYP2C19 446/4885STAT3 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.