SCHEMBL24469712

SCHEMBL24469712

COc1ccc(OC(C(=O)Cl)c2ccccc2-c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
POLB P06746 1/20 0.46
PPARA Q07869 5/20 0.44
PPARG P37231 4/20 0.44
BACE1 P56817 3/20 0.43
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
PKM P14618 1/20 0.41
CYP2C19 P33261 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31532232 1.00 GAA (0.46) GAAPOLBPPARAPPARGBACE1
SCHEMBL30585530 0.89 PPARA (0.49) GAAPOLBPPARAPPARGBACE1
SCHEMBL26978821 0.89 PPARA (0.49) GAAPOLBPPARAPPARGBACE1
SCHEMBL30585539 0.86 ALDH1A1 (0.50) GAAPOLBPPARAPPARGBACE1
SCHEMBL24469716 0.86 ALDH1A1 (0.50) GAAPOLBPPARAPPARGBACE1
SCHEMBL24469705 0.80 PPARG (0.41) GAAPOLBPPARAPPARGALDH1A1
SCHEMBL4592441 0.75 BCAT2 (0.43) GAAPPARAPPARGCYP1A2CYP2C9
SCHEMBL29060122 0.74 POLB (0.42) GAAPOLBPPARAPPARGBACE1
SCHEMBL24469714 0.73 SCN1A (0.46) ALDH1A1CYP1A2
SCHEMBL31532234 0.73 SCN1A (0.46) ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606549-B2 Anticholinergic agents REZUBIO PHARMACEUTICALS CO., LTD (CN) 2026-04-21 US disclosed
US-20240002372-A1 ANTICHOLINERGIC AGENTS REZUBIO PHARMACEUTICALS CO., LTD (CN) 2024-01-04 US disclosed
WO-2022111500-A1 ANTICHOLINERGIC AGENTS REZUBIO PHARMACEUTICALS CO., LTD (CN) 2022-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002372-A1 ANTICHOLINERGIC AGENTS CHRM3, CHRM2, CHRM1 GAA 1816/4885POLB 4166/4885PPARA 2559/4885
US-12606549-B2 Anticholinergic agents CHRM1, CHRNA1, CHRND GAA 4576/4885POLB 4505/4885PPARA 3478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.