Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1142246 | 0.85 | NR3C1 (0.48) | NR3C1 | |
| SCHEMBL2444931 | 0.85 | NR3C1 (0.46) | NR3C1 | |
| SCHEMBL1142453 | 0.77 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL1142450 | 0.77 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL1142026 | 0.76 | NR3C1 (0.44) | NR3C1PGR | |
| SCHEMBL2447009 | 0.76 | NR3C1 (0.50) | NR3C1PGR | |
| SCHEMBL2446994 | 0.76 | NR3C1 (0.50) | NR3C1PGR | |
| SCHEMBL1141826 | 0.76 | NR3C1 (0.47) | NR3C1PGR | |
| SCHEMBL1141814 | 0.76 | NR3C1 (0.49) | NR3C1PGR | |
| SCHEMBL1141822 | 0.76 | NR3C1 (0.47) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896424-B1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2011-09-21 | — | — | EP | claimed |
| EP-1896424-B1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2011-09-21 | — | — | EP | disclosed |