Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454193 | 0.93 | KDM4E (0.45) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL14983302 | 0.92 | KDM4E (0.43) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL502920 | 0.92 | KDM4E (0.47) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL2448597 | 0.84 | KDM4E (0.49) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL29087583 | 0.81 | ALDH1A1 (0.36) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL30522292 | 0.81 | ALDH1A1 (0.36) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL14983295 | 0.80 | KDM4E (0.43) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL2448223 | 0.79 | PTPN11 (0.43) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL14983291 | 0.78 | KDM4E (0.43) | L3MBTL1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL2448227 | 0.76 | KDM4E (0.72) | L3MBTL1KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137869-A1 | LUMINOPHORES | UNIVERSITY OF YORK (UK) | 2013-05-30 | — | — | US | disclosed |
| EP-2547748-A1 | LUMINOPHORES | University of York (GB) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011114095-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2011-09-22 | — | — | WO | disclosed |