Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454193 | 0.86 | KDM4E (0.45) | PTPN11KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL2448597 | 0.86 | KDM4E (0.49) | PTPN11KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL2447002 | 0.79 | L3MBTL1 (0.48) | PTPN11KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL14983295 | 0.79 | KDM4E (0.43) | PTPN11KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL14983291 | 0.79 | KDM4E (0.43) | PTPN11KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL502920 | 0.75 | KDM4E (0.47) | PTPN11KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL2856448 | 0.75 | PTPN11 (0.55) | PTPN11ALDH1A1HPGDPTPN1PTPN6 | |
| SCHEMBL1776071 | 0.75 | PTPN11 (0.55) | PTPN11ALDH1A1HPGDPTPN1PTPN6 | |
| SCHEMBL13957128 | 0.75 | PTPN11 (0.55) | PTPN11ALDH1A1HPGDPTPN1PTPN6 | |
| SCHEMBL28319408 | 0.75 | PTPN11 (0.55) | PTPN11ALDH1A1HPGDPTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137869-A1 | LUMINOPHORES | UNIVERSITY OF YORK (UK) | 2013-05-30 | — | — | US | disclosed |
| EP-2547748-A1 | LUMINOPHORES | University of York (GB) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011114095-A1 | LUMINOPHORES | UNIVERSITY OF YORK (GB) | 2011-09-22 | — | — | WO | disclosed |