SCHEMBL2447083

SCHEMBL2447083

C=CN(CC)C(=O)CCC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
TSHR P16473 2/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
HDAC3 O15379 4/20 0.35
HDAC1 Q13547 4/20 0.35
HDAC2 Q92769 4/20 0.35
HDAC8 Q9BY41 4/20 0.35
FFAR3 O14843 3/20 0.35
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.33
HDAC6 Q9UBN7 1/20 0.31
CTSD P07339 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2447540 0.87 ALDH1A1 (0.50) ALDH1A1TSHRCES2CES1LMNA
SCHEMBL2446211 0.85 ALDH1A1 (0.43) ALDH1A1TSHRCES2CES1LMNA
SCHEMBL2448463 0.84 ALDH1A1 (0.36) ALDH1A1TSHRCES2CES1HDAC3
SCHEMBL2449188 0.84 CES2 (0.45) ALDH1A1TSHRCES2CES1
SCHEMBL2446501 0.84 CES2 (0.45) ALDH1A1TSHRCES2CES1
SCHEMBL2940393 0.84 CES2 (0.45) ALDH1A1TSHRCES2CES1
SCHEMBL2446633 0.84 CES2 (0.45) ALDH1A1TSHRCES2CES1
SCHEMBL2948731 0.84 CES2 (0.45) ALDH1A1TSHRCES2CES1
SCHEMBL2448546 0.84 CES2 (0.45) ALDH1A1TSHRCES2CES1
SCHEMBL11386864 0.83 ALDH1A1 (0.42) ALDH1A1TSHRCES2CES1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10551345-B2 Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2020-02-04 US claimed
US-20170356877-A1 POLY AND COPOLY(N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS, LLC (US) 2017-12-14 US claimed
US-9671367-B2 Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2017-06-06 US claimed
US-20140209461-A1 Poly and Copoly(N-vinylamide)s and Their Use In Capillary Electrophoresis APPLIED BIOSYSTEMS, LLC (US) 2014-07-31 US claimed
EP-2053067-B1 Poly and copoly (N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS LLC (US) 2011-09-14 EP claimed
CN-101724216-A Poly and copolyn(N-vinylamide)s and their use in capillary electrophoresis APPLIED BIOSYSTEMS 2010-06-09 CN claimed
US-20100051461-A1 Poly and Copolyn(N-Vinylamide)s and their use in Capillary Electrophoresis Life Technologies Corporation (US) 2010-03-04 US claimed
US-7641765-B2 Applying slurry containing optical brighteners BASF AKTIENGESELLSCHAFT (DE) 2010-01-05 US claimed
CN-100567339-C (N-vinylamide) polymers and copolymers and their use in capillary electrophoresis APPLERA CORP (US) 2009-12-09 CN claimed
EP-2053067-A1 Poly and copoly (N-vinylamide)s and their use in capillary electrophoresis Applied Biosystems Inc. (US) 2009-04-29 EP claimed
EP-1636279-B1 POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS (US) 2009-02-18 EP claimed
CN-1816573-A (N-vinylamide) polymers and copolymers and their use in capillary electrophoresis APPLERA CORP (US) 2006-08-09 CN claimed
EP-1636279-A1 POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2006-03-22 EP claimed
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides APPLIED BIOSYSTEMS, LLC 2005-02-03 US claimed
WO-2004104054-A1 POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-12-02 WO claimed
CN-120025625-A Foaming composition and application thereof, foaming material and preparation method and application thereof 中国石油化工股份有限公司 2025-05-23 CN disclosed
CN-117986814-A Antibacterial biodegradable expanded beads, preparation method thereof, expanded bead molded body and application thereof 中国石油化工股份有限公司 2024-05-07 CN disclosed
EP-0134921-A1 Copolymer, process for its preparation and its use as a sorbent CASSELLA Aktiengesellschaft (DE) 1985-03-27 EP disclosed
EP-0131179-A1 Copolymer, process for its preparation and its use as a sorbent CASSELLA Aktiengesellschaft (DE) 1985-01-16 EP disclosed
US-4179292-A Light-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1979-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides POLI, PCNA, POLL ALDH1A1 3357/4885TSHR 4259/4885CES2 663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.