Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713149 | 0.93 | GAA (0.44) | GAASMN1; SMN2POLBIGLV6-57ALOX5 | |
| SCHEMBL24470622 | 0.91 | GAA (0.45) | GAASMN1; SMN2POLBIGLV6-57MAPK1 | |
| SCHEMBL29713074 | 0.83 | CASP3 (0.62) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL24470861 | 0.83 | CASP3 (0.62) | GAACASP3SENP8SENP7SENP6 | |
| SCHEMBL24470935 | 0.80 | GAA (0.43) | GAASMN1; SMN2POLBMAPK1MAPK10 | |
| SCHEMBL24470936 | 0.80 | GAA (0.43) | GAASMN1; SMN2POLBMAPK1MAPK10 | |
| SCHEMBL29713010 | 0.80 | GAA (0.44) | GAAIGLV6-57MAPK1MAPK10KDM4E | |
| SCHEMBL24470933 | 0.79 | GAA (0.47) | GAASMN1; SMN2POLBALOX5KDM4E | |
| SCHEMBL24485157 | 0.79 | CASP3 (0.46) | GAASMN1; SMN2POLBMAPK1MAPK10 | |
| SCHEMBL24470742 | 0.79 | SLC26A4 (0.52) | GAASMN1; SMN2POLBMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |