Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGDS | O60760 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24470623 | 0.85 | SLC26A4 (0.50) | GAAPOLBSMN1; SMN2HPGDSTSHR | |
| SCHEMBL29713109 | 0.85 | CASP3 (0.60) | TSHRHTTL3MBTL1LMNAMAPT | |
| SCHEMBL24470575 | 0.85 | CASP3 (0.60) | TSHRHTTL3MBTL1LMNAMAPT | |
| SCHEMBL24470772 | 0.85 | CASP3 (0.60) | TSHRHTTL3MBTL1LMNAMAPT | |
| SCHEMBL24470581 | 0.85 | CASP3 (0.60) | TSHRHTTL3MBTL1LMNAMAPT | |
| SCHEMBL29712964 | 0.85 | CASP3 (0.60) | TSHRHTTL3MBTL1LMNAMAPT | |
| SCHEMBL29629636 | 0.84 | MAPT (0.47) | GAAPOLBSMN1; SMN2HPGDSTSHR | |
| SCHEMBL24484797 | 0.83 | CASP3 (0.46) | GAAPOLBSMN1; SMN2HPGDSTSHR | |
| SCHEMBL24470896 | 0.83 | ANO1 (0.50) | GAASMN1; SMN2TSHRHTTL3MBTL1 | |
| SCHEMBL24485179 | 0.83 | CASP3 (0.46) | GAASMN1; SMN2HPGDSTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |