Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 13/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24472787 | 0.88 | HDAC6 (0.58) | HDAC3HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL24473211 | 0.87 | HDAC6 (0.54) | HDAC3HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL24472776 | 0.82 | HDAC6 (0.59) | HDAC3HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL24473208 | 0.78 | HDAC3 (0.54) | HDAC3HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL22483035 | 0.77 | HDAC6 (0.63) | HDAC3HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL20847669 | 0.77 | AGER (0.40) | HDAC6ALDH1A1LMNAKMT2A | |
| SCHEMBL24473070 | 0.77 | HDAC6 (0.61) | HDAC3HDAC6HDAC8HDAC11 | |
| SCHEMBL20847506 | 0.76 | EPHX1 (0.43) | HDAC3HDAC6HDAC8HDAC11ALDH1A1 | |
| SCHEMBL20847575 | 0.76 | AGER (0.42) | ALDH1A1LMNAKMT2A | |
| SCHEMBL20847602 | 0.76 | AGER (0.38) | HDAC3HDAC6HDAC8ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169598-A1 | HALOGENATED PHENYLSULFONAMIDE HYDROXAMIC ACID COMPOUNDS, COMPOSITIONS AND USES THEREOF AS SELECTIVE HDAC6 INHIBITORS | 2681603 ONTARIO INC. (CA) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169598-A1 | HALOGENATED PHENYLSULFONAMIDE HYDROXAMIC ACID COMPOUNDS, COMPOSITIONS AND USES THEREOF AS SELECTIVE HDAC6 INHIBITORS | HDAC6, HDAC1, HDAC11 | HDAC3 4/4885HDAC6 1/4885HDAC8 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.