Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847575 | 0.98 | AGER (0.42) | AGERMTNR1AALDH1A1KMT2AMEN1 | |
| SCHEMBL20847602 | 0.98 | AGER (0.38) | AGERMTNR1AALDH1A1KMT2AMEN1 | |
| SCHEMBL20847492 | 0.84 | HDAC8 (0.37) | AGERMTNR1AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL20847639 | 0.82 | ELOVL1 (0.39) | KMT2AMEN1POLBSLC6A2SLC6A4 | |
| SCHEMBL20847664 | 0.82 | ESR1 (0.38) | ALDH1A1NSD2HDAC6 | |
| SCHEMBL20847604 | 0.82 | SLC6A2 (0.38) | AGERHRH3POLBSLC6A2SLC6A4 | |
| SCHEMBL20847477 | 0.81 | SLC6A2 (0.39) | ALDH1A1SLC6A2SLC6A4HDAC6PSEN1 | |
| SCHEMBL20847642 | 0.79 | SLC6A4 (0.35) | ALDH1A1KMT2AMEN1POLBSLC6A2 | |
| SCHEMBL20847650 | 0.79 | ALDH1A1 (0.35) | ALDH1A1LMNAHDAC6CYP3A4CYP2D6 | |
| SCHEMBL20847637 | 0.78 | SLC6A2 (0.39) | AGERMTNR1AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019056120-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2019-03-28 | — | — | WO | disclosed |