Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 9/20 | 0.59 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.45 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17922947 | 0.83 | SSTR4 (0.51) | SSTR4TNKSTNKS2SSTR1SSTR2 | |
| SCHEMBL29542994 | 0.81 | SSTR4 (0.48) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL8097215 | 0.81 | SSTR4 (0.60) | SSTR4LMNASMN1; SMN2SCN9AKDM4E | |
| SCHEMBL29541761 | 0.80 | SSTR4 (0.49) | SSTR4SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL18347306 | 0.78 | SSTR4 (0.55) | SSTR4TSHRSCN9AKHKKDM4E | |
| SCHEMBL4963259 | 0.78 | TNKS (0.51) | SSTR4SMN1; SMN2TNKSTNKS2F10 | |
| SCHEMBL21214136 | 0.78 | SLC6A1 (0.53) | SSTR4SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL21214198 | 0.78 | SLC6A1 (0.53) | SSTR4SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL21214016 | 0.78 | SLC6A1 (0.53) | SSTR4SLC6A1SLC6A11TSHRLMNA | |
| Hydrochloric Acid SCHEMBL18336412 | 0.77 | SSTR4 (0.53) | SSTR4TSHRSCN9AKHKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2011-09-07 | — | — | EP | disclosed |