Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.42 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451469 | 0.79 | TNKS (0.58) | TNKSTNKS2HTR6ROCK2ALDH1A1 | |
| SCHEMBL2447500 | 0.78 | SSTR4 (0.59) | TNKSTNKS2KMT2AF10KHK | |
| SCHEMBL2447263 | 0.76 | TNKS (0.58) | TNKSTNKS2HTR6MEN1KMT2A | |
| SCHEMBL3416580 | 0.76 | SMN1; SMN2 (0.71) | TNKSTNKS2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1318173 | 0.76 | HPGD (0.66) | TNKSTNKS2MEN1KMT2AF10 | |
| SCHEMBL2446479 | 0.76 | HPGD (0.66) | TNKSTNKS2MEN1KMT2AF10 | |
| SCHEMBL1318166 | 0.76 | HPGD (0.66) | TNKSTNKS2MEN1KMT2AF10 | |
| Hydrochloric Acid SCHEMBL4033476 | 0.74 | HPGD (0.64) | TNKSTNKS2MEN1KMT2AF10 | |
| SCHEMBL24016844 | 0.74 | RXFP1 (0.59) | TNKSTNKS2HTR6RXFP1F10 | |
| SCHEMBL4963033 | 0.73 | TNKS (0.55) | TNKSTNKS2HTR6RXFP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | disclosed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | disclosed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |