SCHEMBL24475111

SCHEMBL24475111

CC(C)(C)c1nc(-c2ccc(-c3ccccc3)cc2)c2cc(CC(C)(C)c3nc(-c4ccccc4)c4ccccc4n3)ccc2n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
NUDT1 P36639 5/20 0.39
ADORA2A P29274 2/20 0.38
KDM4E B2RXH2 4/20 0.36
ALDH1A1 P00352 3/20 0.36
CCNE2 O96020 1/20 0.36
CDK4 P11802 1/20 0.36
CCND1 P24385 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK2 P24941 1/20 0.36
MAPT P10636 3/20 0.36
LMNA P02545 2/20 0.36
PLA2G1B P04054 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
KLK7 P49862 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18232171 0.83 ADORA2A (0.51) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL23920595 0.82 MMP12 (0.35) MEN1KMT2ANUDT1KDM4EALDH1A1
SCHEMBL23183914 0.81 MEN1 (0.41) MEN1KMT2AATMNUDT1ALDH1A1
SCHEMBL16520903 0.80 ADORA2A (0.55) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL21086068 0.78 ADORA2A (0.30) ADORA2AKDM4EALDH1A1MAPT
SCHEMBL18232159 0.76 ADORA2A (0.46) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL25885515 0.76 SCN9A (0.43) MEN1KMT2AADORA2ACCNE2CCNE1
SCHEMBL21888187 0.75 SYK (0.35) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL25877803 0.75 TNKS (0.51) MEN1KMT2AATMNUDT1ADORA2A
SCHEMBL24700745 0.74 MMP12 (0.33) MEN1KMT2AKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220173330-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LEF1, ODC1, OR10J3 MEN1 1350/4885KMT2A 2221/4885ATM 2614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.