Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.58 |
| ▸ | RARG | P13631 | 4/20 | 0.58 |
| ▸ | RARA | P10276 | 3/20 | 0.58 |
| ▸ | RXRA | P19793 | 3/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703376 | 0.90 | RARB (0.60) | RARBRARGRARARXRAALOX5 | |
| SCHEMBL9202781 | 0.90 | RARB (0.60) | RARBRARGRARARXRAALOX5 | |
| SCHEMBL703377 | 0.90 | RARB (0.60) | RARBRARGRARARXRAALOX5 | |
| SCHEMBL20839002 | 0.88 | ALOX5 (0.60) | RARBRARGRARARXRAALOX5 | |
| SCHEMBL20839001 | 0.88 | ALOX5 (0.60) | RARBRARGRARARXRAALOX5 | |
| SCHEMBL10044151 | 0.87 | RARB (0.54) | RARBRARGRARARXRAALOX5 | |
| SCHEMBL18084341 | 0.87 | RARB (0.54) | RARBRARGRARARXRAALOX5 | |
| SCHEMBL1105236 | 0.87 | RARB (0.54) | RARBRARGRARARXRAALOX5 | |
| SCHEMBL13554229 | 0.86 | RARB (0.56) | RARBRARGRARARXRAALOX5 | |
| SCHEMBL16670830 | 0.86 | RARB (0.56) | RARBRARGRARARXRAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112118-A1 | REDUCTION BY A SILANE IN THE PRESENCE OF ZINC CATALYST | FIRMENICH SA (CH) | 2022-06-02 | — | — | WO | disclosed |