Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.60 |
| ▸ | RARG | P13631 | 6/20 | 0.60 |
| ▸ | RXRA | P19793 | 6/20 | 0.60 |
| ▸ | RARA | P10276 | 5/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202781 | 1.00 | RARB (0.60) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL703376 | 1.00 | RARB (0.60) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL24475285 | 0.90 | RARB (0.58) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL9016204 | 0.88 | ALOX5 (0.59) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL9016206 | 0.88 | ALOX5 (0.59) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL10044151 | 0.86 | RARB (0.54) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL18084341 | 0.86 | RARB (0.54) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL1105236 | 0.86 | RARB (0.54) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL16670830 | 0.85 | RARB (0.56) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL13554229 | 0.85 | RARB (0.56) | RARBRARGRXRARARATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217362-A1 | REDUCTION BY A SILANE IN THE PRESENCE OF ZINC CATALYST | Firmenich SA (CH) | 2023-08-02 | — | — | EP | claimed |
| WO-2022112118-A1 | REDUCTION BY A SILANE IN THE PRESENCE OF ZINC CATALYST | FIRMENICH SA (CH) | 2022-06-02 | — | — | WO | claimed |
| EP-3060546-B1 | PROCESSES FOR THE PREPARATION OF UNSATURATED ESTERS | INT FLAVORS & FRAGRANCES INC (US) | 2019-02-13 | — | — | EP | claimed |
| EP-4217362-B1 | REDUCTION BY A SILANE IN THE PRESENCE OF ZINC CATALYST | FIRMENICH & CIE (CH) | 2026-03-18 | — | — | EP | disclosed |
| US-20240010585-A1 | REDUCTION BY A SILANE IN THE PRESENCE OF ZINC CATALYST | FIRMENICH SA (CH) | 2024-01-11 | — | — | US | disclosed |
| US-11858948-B2 | Hydrogenation of carbonyls with tetradentate PNNP ligand ruthenium complexes | FIRMENICH SA (CH) | 2024-01-02 | — | — | US | disclosed |
| EP-4217362-A1 | REDUCTION BY A SILANE IN THE PRESENCE OF ZINC CATALYST | Firmenich SA (CH) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022112118-A1 | REDUCTION BY A SILANE IN THE PRESENCE OF ZINC CATALYST | FIRMENICH SA (CH) | 2022-06-02 | — | — | WO | disclosed |
| EP-3700914-B1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | FIRMENICH & CIE (CH) | 2022-02-02 | — | — | EP | disclosed |
| US-20200399299-A1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2020-12-24 | — | — | US | disclosed |
| EP-3700914-A1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | Firmenich SA (CH) | 2020-09-02 | — | — | EP | disclosed |
| EP-1868965-A1 | HYDROGENATION OF ESTERS WITH RU/TETRADENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2007-12-26 | — | — | EP | disclosed |
| EP-1868964-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2007-12-26 | — | — | EP | disclosed |
| EP-1773799-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY-ACTIVE COMPOUNDS | Givaudan SA (CH) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006106484-A1 | HYDROGENATION OF ESTERS WITH RU/TETRADENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006106483-A1 | HYDROGENATION OF ESTERS WITH RU/BIDENTATE LIGANDS COMPLEXES | FIRMENICH SA (CH) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006010287-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY-ACTIVE COMPOUNDS | GIVAUDAN SA (CH) | 2006-02-02 | — | — | WO | disclosed |
| EP-0525579-B1 | Process for preparing substituted hexemic acids | GIVAUDAN ROURE INT (CH) | 1995-09-20 | — | — | EP | disclosed |
| US-5292902-A | Process for the manufacture of odorants and intermediates used therein | GIVAUDAN-ROURE CORPORATION (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0525579-A2 | Process for preparing substituted hexemic acids | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1993-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240010585-A1 | REDUCTION BY A SILANE IN THE PRESENCE OF ZINC CATALYST | HDAC10, AKR1B10, ADH1A | RARB 3085/4885RARG 3640/4885RXRA 4166/4885 |
| US-11858948-B2 | Hydrogenation of carbonyls with tetradentate PNNP ligand ruthenium complexes | ADH1C, ADH1A, ADH5 | RARB 2983/4885RARG 2648/4885RXRA 1872/4885 |
| US-20200399299-A1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | ADH1C, ADH1A, ADH5 | RARB 2983/4885RARG 2648/4885RXRA 1872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.