Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 17/20 | 0.57 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15175749 | 0.98 | HCRTR1 (0.59) | HCRTR1HCRTR2TSHRRECQLSCN1A | |
| SCHEMBL2448801 | 0.92 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL2445627 | 0.88 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL3415643 | 0.87 | HCRTR1 (0.46) | HCRTR1HCRTR2TSHRRECQL | |
| SCHEMBL2930541 | 0.87 | HCRTR1 (0.46) | HCRTR1HCRTR2TSHRRECQL | |
| SCHEMBL15174295 | 0.86 | HCRTR1 (0.59) | HCRTR1HCRTR2TSHRRECQLSCN1A | |
| SCHEMBL2444050 | 0.86 | HCRTR1 (0.47) | HCRTR1HCRTR2TSHR | |
| SCHEMBL2447671 | 0.82 | HCRTR1 (0.48) | HCRTR1HCRTR2TSHRRECQL | |
| SCHEMBL2447675 | 0.82 | HCRTR1 (0.48) | HCRTR1HCRTR2TSHRRECQL | |
| SCHEMBL2450567 | 0.82 | HCRTR1 (0.42) | HCRTR1HCRTR2TSHRRECQLSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164847-B1 | 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-09-14 | — | — | EP | claimed |