SCHEMBL2447736

SCHEMBL2447736

CC(C)c1cc(C2(c3ccc(Oc4ccc(N)cc4C(C)(C)C)c(C(C)C)c3)c3ccccc3-c3ccccc32)ccc1Oc1ccc(N)cc1C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
OPRK1 P41145 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
PDK2 Q15119 2/20 0.33
P2RX3 P56373 1/20 0.30
P2RX2 Q9UBL9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2444649 0.96 KDM4E (0.43) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2444873 0.90 KDM4E (0.42) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2445382 0.90 KDM4E (0.50) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2440276 0.90 SMN1; SMN2 (0.50) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL3874551 0.89 KDM4E (0.40) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2446598 0.86 KDM4E (0.42) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2448875 0.85 ESR1 (0.46) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL2446277 0.85 LMNA (0.46) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL29418397 0.85 LMNA (0.46) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25225771 0.84 KDM4E (0.40) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed
EP-2128193-B1 POROUS POLYIMIDE IBIDEN CO LTD (JP) 2013-06-19 EP disclosed
US-8022110-B2 Porous polyimide IBIDEN CO., LTD. (JP) 2011-09-20 US disclosed
US-20100048745-A1 POROUS POLYIMIDE IBIDEN CO., LTD (JP) 2010-02-25 US disclosed
EP-2128193-A1 POROUS POLYIMIDE Ibiden Co., Ltd. (JP) 2009-12-02 EP disclosed