SCHEMBL2446277

SCHEMBL2446277

Cc1cc(N)ccc1Oc1ccc(C2(c3ccc(Oc4ccc(N)cc4C)c(C(C)C)c3)c3ccccc3-c3ccccc32)cc1C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
OPRK1 P41145 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
PDK2 Q15119 2/20 0.32
ALDH1A1 P00352 1/20 0.32
P2RX3 P56373 4/20 0.32
P2RX2 Q9UBL9 4/20 0.32
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29418397 1.00 LMNA (0.46) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL25251979 0.95 ESR1 (0.46) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL2440276 0.93 SMN1; SMN2 (0.50) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL2443598 0.89 ESR1 (0.45) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL29418392 0.89 MAPT (0.54) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL2445179 0.89 MAPT (0.54) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL3874336 0.88 LMNA (0.42) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL2446794 0.86 SMN1; SMN2 (0.43) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL2443500 0.85 SMN1; SMN2 (0.51) LMNAMAPTKDM4EMEN1OPRK1
SCHEMBL2447736 0.85 KDM4E (0.43) LMNAMAPTKDM4EMEN1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed
EP-2128193-B1 POROUS POLYIMIDE IBIDEN CO LTD (JP) 2013-06-19 EP disclosed
US-8022110-B2 Porous polyimide IBIDEN CO., LTD. (JP) 2011-09-20 US disclosed
US-20100048745-A1 POROUS POLYIMIDE IBIDEN CO., LTD (JP) 2010-02-25 US disclosed
EP-2128193-A1 POROUS POLYIMIDE Ibiden Co., Ltd. (JP) 2009-12-02 EP disclosed