Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | PDE8A | O60658 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24477397 | 1.00 | RAB9A (0.45) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL24477382 | 1.00 | RAB9A (0.45) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL24477378 | 0.91 | RAB9A (0.46) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL24477380 | 0.91 | KMT2A (0.44) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL24477384 | 0.91 | KMT2A (0.44) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL24477398 | 0.91 | KMT2A (0.44) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL24477388 | 0.89 | KMT2A (0.43) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL24477393 | 0.89 | KDM4E (0.51) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL24477379 | 0.89 | KDM4E (0.51) | RAB9ANPC1KDM4EALDH1A1HPGD | |
| SCHEMBL24477385 | 0.89 | KDM4E (0.51) | RAB9ANPC1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111473-A1 | COMPOUNDS AS MRGPRX2 ANTAGONISTS | BIOARDIS LLC (US) | 2022-06-02 | — | — | WO | disclosed |
| WO-2022111473-A1 | COMPOUNDS AS MRGPRX2 ANTAGONISTS | BIOARDIS LLC (US) | 2022-06-02 | — | — | WO | disclosed |