Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15284485 | 0.89 | MAOB (0.53) | SLC1A1MAOBCA1PPARAALDH1A1 | |
| SCHEMBL1050077 | 0.86 | SLC1A1 (0.41) | SLC1A1MAOBCA1PPARAALDH1A1 | |
| SCHEMBL19357526 | 0.81 | LMNA (0.45) | PPARASMN1; SMN2ALOX15PRKCAPRKCD | |
| SCHEMBL4064873 | 0.81 | ALPI (0.43) | ALDH1A1CYP3A4TSHRPOLBFOLH1 | |
| SCHEMBL5066181 | 0.81 | ALPI (0.43) | ALDH1A1CYP3A4TSHRPOLBFOLH1 | |
| SCHEMBL18344466 | 0.81 | ALPI (0.43) | ALDH1A1CYP3A4TSHRPOLBFOLH1 | |
| SCHEMBL19517671 | 0.81 | NR1H2 (0.47) | SLC1A1MAOBCA1PPARAALDH1A1 | |
| SCHEMBL19517669 | 0.81 | NR1H2 (0.47) | SLC1A1MAOBCA1PPARAALDH1A1 | |
| SCHEMBL2207393 | 0.78 | CTSS (0.46) | SLC1A1CA1PPARAALDH1A1CA2 | |
| SCHEMBL5065706 | 0.78 | KMT2A (0.47) | ALDH1A1SMN1; SMN2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026273-B2 | 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-27 | — | — | US | disclosed |