SCHEMBL2447989

SCHEMBL2447989

Nc1ccc2c(c1)=c1cc(N)ccc1=2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ MAPT P10636 3/20 0.47
▸ CYP3A4 P08684 6/20 0.44
▸ CASP1 P29466 4/20 0.44
▸ RECQL P46063 1/20 0.44
▸ ALDH1A1 P00352 5/20 0.43
▸ TSHR P16473 3/20 0.43
▸ HSD17B10 Q99714 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ CASP7 P55210 1/20 0.39
▸ HBB P68871 1/20 0.39
▸ HIF1A Q16665 1/20 0.39
▸ F2 P00734 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ CHRM2 P08172 1/20 0.39
▸ HTR1A P08908 1/20 0.39
▸ ADRA2A P08913 1/20 0.39
▸ ADORA3 P0DMS8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10825617 1.00 MEN1 (0.47) MEN1KMT2AMAPTCYP3A4CASP1
SCHEMBL1577950 0.91 ALDH1A1 (0.48) MEN1KMT2AMAPTCYP3A4CASP1
SCHEMBL145891 0.67 ALDH1A1 (0.77) MEN1KMT2AMAPTCYP3A4CASP1
SCHEMBL29367325 0.67 ALDH1A1 (0.77) MEN1KMT2AMAPTCYP3A4CASP1
SCHEMBL320609 0.66 MEN1 (1.00) MEN1KMT2AMAPTCYP3A4CASP1
SCHEMBL27981 0.66 — —
SCHEMBL5472428 0.64 CYP3A4 (0.86) MEN1KMT2AMAPTCYP3A4CASP1
SCHEMBL202182 0.64 ALDH1A1 (0.72) MEN1KMT2AMAPTCYP3A4CASP1
SCHEMBL10825616 0.64 PTPRC (0.64) MEN1KMT2AMAPTCYP3A4CASP1
SCHEMBL18799195 0.64 PTPRC (0.64) MEN1KMT2AMAPTCYP3A4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11520186-B2 Liquid crystal display and method for manufacturing same NISSAN CHEMICAL CORPORATION (JP) 2022-12-06 — — US disclosed
US-20200201126-A1 LIQUID CRYSTAL DISPLAY AND METHOD FOR MANUFACTURING SAME NISSAN CHEMICAL CORP (JP) 2020-06-25 — — US disclosed
US-20160377925-A1 LIQUID CRYSTAL DISPLAY AND METHOD FOR MANUFACTURING SAME NISSAN CHEMICAL CORPORATION (JP) 2016-12-29 — — US disclosed
US-9405152-B2 Liquid crystal display and method for manufacturing same JAPAN DISPLAY INC. (JP) 2016-08-02 — — US disclosed
US-20140248445-A1 LIQUID CRYSTAL DISPLAY AND METHOD FOR MANUFACTURING SAME JAPAN DISPLAY INC. (JP) 2014-09-04 — — US disclosed
US-8758871-B2 Liquid crystal display and method for manufacturing same JAPAN DISPLAY INC. (JP) 2014-06-24 — — US disclosed
US-8025939-B2 Liquid crystal display and method for manufacturing same HITACHI DISPLAYS, LTD. (JP) 2011-09-27 — — US disclosed
US-20100225865-A1 LIQUID CRYSTAL DISPLAY AND METHOD FOR MANUFACTURING SAME NISSAN CHEMICAL CORPORATION (JP) 2010-09-09 — — US disclosed
US-7718234-B2 in-plane switching; improved image quality; alignment control film contains polyamic acid or polyimide comprising cyclobutanetetracarboxylic acid dianhydride and/or its derivative and aromatic diamine HITACHI DISPLAYS, LTD. (JP) 2010-05-18 — — US disclosed
US-20060061719-A1 in-plane switching; improved image quality; alignment control film contains polyamic acid or polyimide comprising cyclobutanetetracarboxylic acid dianhydride and/or its derivative and aromatic diamine NISSAN CHEMICAL CORPORATION (JP) 2006-03-23 — — US disclosed
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