SCHEMBL145891

SCHEMBL145891

Nc1ccc2cc(N)ccc2c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.77
CYP3A4 P08684 5/20 0.77
HSD17B10 Q99714 3/20 0.77
CASP1 P29466 4/20 0.72
CASP7 P55210 2/20 0.72
HBB P68871 2/20 0.72
HIF1A Q16665 2/20 0.72
ALOX15 P16050 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
MEN1 O00255 5/20 0.68
KMT2A Q03164 5/20 0.68
KDM4E B2RXH2 5/20 0.68
MAPT P10636 5/20 0.68
HTT P42858 4/20 0.55
LMNA P02545 3/20 0.55
F2 P00734 1/20 0.55
CHRM2 P08172 1/20 0.55
HTR1A P08908 1/20 0.55
ADRA2A P08913 1/20 0.55
ADORA3 P0DMS8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367325 1.00 ALDH1A1 (0.77) ALDH1A1CYP3A4HSD17B10CASP1CASP7
Fluoride SCHEMBL27620141 0.96 ALDH1A1 (0.72) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL2893484 0.93 ALDH1A1 (0.83) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL29165604 0.93 ALDH1A1 (0.83) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL3412594 0.93 ALDH1A1 (0.78) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL30413338 0.93 ALDH1A1 (0.83) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL442351 0.93 ALDH1A1 (0.83) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL202182 0.89 ALDH1A1 (0.72) ALDH1A1CYP3A4HSD17B10CASP1CASP7
SCHEMBL29468144 0.89 ALDH1A1 (0.72) ALDH1A1CYP3A4HSD17B10CASP1CASP7
Naphthylamine SCHEMBL76713 0.87 ALDH1A1 (1.00) ALDH1A1CYP3A4HSD17B10CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4225 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333579-A1 COMPOSITION AND PACKAGE STRUCTURE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2025-10-30 US claimed
US-20250215292-A1 ADHESIVE AND MULTILAYER STRUCTURE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2025-07-03 US claimed
CN-115275028-B Preparation method of perovskite battery 安徽华晟新能源科技股份有限公司 2025-04-04 CN claimed
WO-2024212818-A1 PREPARATION METHOD FOR ANTI-STATIC POLYIMIDE RESIN 黄山聚鑫新材料有限公司 2024-10-17 WO claimed
US-12060457-B2 Resin composition for display substrate, resin film for display substrate and laminate body containing this, image display device, organic EL display, and manufacturing method of these TORAY INDUSTRIES, INC. (JP) 2024-08-13 US claimed
US-20240262963-A1 POLYIMIDE COMPOSITION, METHOD FOR PREPARING THE SAME, POLYIMIDE FILM AND FLEXIBLE COPPER CLAD LAMINATE NEXFLEX CO., LTD. (KR) 2024-08-08 US claimed
CN-118344590-A Polyamic acid containing trifluoro and amide bonds, and preparation method and application thereof 株洲时代新材料科技股份有限公司 2024-07-16 CN claimed
CN-118311127-A Preparation method and mass spectrum imaging application of potential-driven COF self-assembly modified nano substrate 华南农业大学 2024-07-09 CN claimed
US-20240218170-A1 POLYIMIDE RESIN COMPOSITION, POLYIMIDE-BASED ADHESIVE COMPOSITION, POLYIMIDE ADHESIVE FILM, AND FLEXIBLE METAL CLAD LAMINATE FILM NEXFLEX CO., LTD. (KR) 2024-07-04 US claimed
CN-115232017-B Compound, resin and preparation method and application thereof 华为技术有限公司 2024-06-18 CN claimed
US-4485234-A FROM DIAMINE, DIANHYDRIDE, AND DIAMINECARBONAMIDE HITACHI CHEMICAL COMPANY, LTD. (JP) 1984-11-27 US claimed
US-4447596-A REACTING DIAMINE AND DIANHYDRIDE AT LOW TEMPERATURE, THEN ADJUSTMENT OF VISCOSITY BY HEATING HITACHI CHEMICAL COMPANY, LTD. (JP) 1984-05-08 US claimed
EP-0099997-A1 Process for producing aromatic polyamide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-02-08 EP claimed
US-4381210-A Process for producing polyimide tubes NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1983-04-26 US claimed
EP-0073304-A1 A method of storing data in a storage device International Business Machines Corporation (US) 1983-03-09 EP claimed
US-4347286-A Heat fusible polyimide compound films and process for producing the same NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-08-31 US claimed
US-4338427-A HEAT, WEAR, AND CHEMICAL RESISTANCE HITACHI CHEMICAL COMPANY LTD. (JP) 1982-07-06 US claimed
US-4172937-A REACTION OF A DIALDEHYDE AND DIAMINE IN A PHENOLIC COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-10-30 US claimed
US-4018742-A Imide-ring containing polyester and wire enamel containing same NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-04-19 US claimed
US-3975330-A Imide-modified polyester resin and wire enamel containing the imide-modified polyester resin NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-08-17 US claimed