SCHEMBL2448137

SCHEMBL2448137

C=CCN(CC=C)C(=O)C(C)=CC(N)C=C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.38
ALDH1A1 P00352 1/20 0.36
F2 P00734 3/20 0.33
KLK1 P06870 3/20 0.33
PRSS1 P07477 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6530072 0.71 ALDH1A1 (0.38) ALDH1A1
SCHEMBL45578 0.71 TSHR (0.34) ALDH1A1
SCHEMBL531565 0.71 ALDH1A1 (0.38) ALDH1A1
SCHEMBL8600903 0.70 ALDH1A1 (0.37) DPP4ALDH1A1F2KLK1PRSS1
Hydrochloric Acid SCHEMBL6419361 0.70 ALDH1A1 (0.36) ALDH1A1
SCHEMBL569156 0.70 ALDH1A1 (0.56) DPP4ALDH1A1
SCHEMBL11131389 0.69 TDP1 (0.35) ALDH1A1
SCHEMBL131046 0.69 ALDH1A1 (0.46) DPP4ALDH1A1F2KLK1PRSS1
SCHEMBL2448142 0.68 ALDH1A1 (0.35) DPP4ALDH1A1F2KLK1PRSS1
SCHEMBL8530632 0.68 ALDH1A1 (0.39) DPP4ALDH1A1F2KLK1PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1844127-B1 OIL COMPOSITION FOR LUBRICATING AN EGR EQUIPPED DIESEL ENGINE AND AN EGR EQUIPPED DIESEL ENGINE COMPRISING SAME EVONIK OIL ADDITIVES GMBH (DE) 2017-12-06 EP disclosed
US-8012919-B2 Oil composition for lubricating an EGR equipped diesel engine and an EGR equipped diesel engine comprising same EVONIK ROHMAX ADDITIVES GMBH (DE) 2011-09-06 US disclosed
US-20090270287-A1 OIL COMPOSITION FOR LUBRICATING AN EGR EQUIPPED DIESEL ENGINE AND AN EGR EQUIPPED DIESEL ENGINE COMPRISING SAME ROHMAX ADDITIVES GMBH (DE) 2009-10-29 US disclosed
US-7560420-B2 Oil composition for lubricating an EGR equipped diesel engine and an EGR equipped diesel engine comprising same ROHMAX ADDITIVES GMBH (DE) 2009-07-14 US disclosed
EP-1844127-A2 OIL COMPOSITION FOR LUBRICATING AN EGR EQUIPPED DIESEL ENGINE AND AN EGR EQUIPPED DIESEL ENGINE COMPRISING SAME Rohmax Additives GmbH (DE) 2007-10-17 EP disclosed
WO-2006066649-A2 OIL COMPOSITION FOR LUBRICATING AN EGR EQUIPPED DIESEL ENGINE AND AN EGR EQUIPPED DIESEL ENGINE COMPRISING SAME ROHMAX ADDITIVES GMBH (DE) 2006-06-29 WO disclosed
US-20060142168-A1 Oil composition for lubricating an EGR equipped diesel engine and an EGR equipped diesel engine comprising same ROHMAX ADDITIVES GMBH (DE) 2006-06-29 US disclosed