SCHEMBL2448142

SCHEMBL2448142

C=CCN(CC=C)C(=O)C(C)=CCC=CN

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
F2 P00734 4/20 0.35
KLK1 P06870 4/20 0.35
PRSS1 P07477 4/20 0.35
MAPT P10636 1/20 0.33
DPP4 P27487 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6259609 0.77
SCHEMBL8600903 0.76 ALDH1A1 (0.37) ALDH1A1F2KLK1PRSS1DPP4
SCHEMBL8530632 0.73 ALDH1A1 (0.39) ALDH1A1F2KLK1PRSS1DPP4
SCHEMBL45579 0.70 AKR1C3 (0.34)
SCHEMBL1201124 0.70 TDP1 (0.31)
SCHEMBL569156 0.69 ALDH1A1 (0.56) ALDH1A1MAPTDPP4SMN1; SMN2
SCHEMBL2448137 0.68 DPP4 (0.38) ALDH1A1F2KLK1PRSS1DPP4
SCHEMBL131046 0.68 ALDH1A1 (0.46) ALDH1A1F2KLK1PRSS1MAPT
SCHEMBL18435766 0.67 ALDH1A1 (0.42) ALDH1A1MAPTDPP4SMN1; SMN2
SCHEMBL5261157 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1844127-B1 OIL COMPOSITION FOR LUBRICATING AN EGR EQUIPPED DIESEL ENGINE AND AN EGR EQUIPPED DIESEL ENGINE COMPRISING SAME EVONIK OIL ADDITIVES GMBH (DE) 2017-12-06 EP disclosed
US-8012919-B2 Oil composition for lubricating an EGR equipped diesel engine and an EGR equipped diesel engine comprising same EVONIK ROHMAX ADDITIVES GMBH (DE) 2011-09-06 US disclosed
US-20090270287-A1 OIL COMPOSITION FOR LUBRICATING AN EGR EQUIPPED DIESEL ENGINE AND AN EGR EQUIPPED DIESEL ENGINE COMPRISING SAME ROHMAX ADDITIVES GMBH (DE) 2009-10-29 US disclosed
US-7560420-B2 Oil composition for lubricating an EGR equipped diesel engine and an EGR equipped diesel engine comprising same ROHMAX ADDITIVES GMBH (DE) 2009-07-14 US disclosed
EP-1844127-A2 OIL COMPOSITION FOR LUBRICATING AN EGR EQUIPPED DIESEL ENGINE AND AN EGR EQUIPPED DIESEL ENGINE COMPRISING SAME Rohmax Additives GmbH (DE) 2007-10-17 EP disclosed
WO-2006066649-A2 OIL COMPOSITION FOR LUBRICATING AN EGR EQUIPPED DIESEL ENGINE AND AN EGR EQUIPPED DIESEL ENGINE COMPRISING SAME ROHMAX ADDITIVES GMBH (DE) 2006-06-29 WO disclosed
US-20060142168-A1 Oil composition for lubricating an EGR equipped diesel engine and an EGR equipped diesel engine comprising same ROHMAX ADDITIVES GMBH (DE) 2006-06-29 US disclosed