Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 7/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1836974 | 1.00 | AKR1C3 (0.61) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL19868903 | 1.00 | AKR1C3 (0.61) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL3516198 | 0.83 | NPC1 (0.79) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL2511695 | 0.83 | NPC1 (0.79) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL664284 | 0.83 | NPC1 (0.79) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL11099195 | 0.83 | AKR1C3 (0.66) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL1944663 | 0.83 | AKR1C3 (0.56) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| Bicarbonate SCHEMBL1720488 | 0.83 | AKR1C3 (0.63) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| Bicarbonate SCHEMBL7573346 | 0.83 | AKR1C3 (0.63) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL15043523 | 0.82 | NPC1 (0.47) | AKR1C3AKR1C1NPC1RAB9ASLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118851895-A | Method for continuously synthesizing 4-acetylcyclohexylbenzene by using microchannel reactor | 品恩赢创(苏州)新材料科技有限公司 | 2024-10-29 | — | — | CN | claimed |
| CN-112341320-A | Novel synthesis method of p- (trans-4-hydroxycyclohexyl) phenol | 烟台丰鲁精细化工有限责任公司 | 2021-02-09 | — | — | CN | claimed |
| US-20040224954-A1 | Substituted 1H-quinoxalin-2-one compounds and substituted 4-aryl- and 4-heteroarylcyclohexane compounds | GRUNENTHAL GMBH (DE) | 2004-11-11 | — | — | US | claimed |
| EP-1444212-A1 | SUBSTITUTED (1H)-QUINOXALIN-2-ONE COMPOUNDS AND SUBSTITUTED 4-ARYL- AND 4-HETEROARYLCYCLOHEXANE COMPOUNDS | Grünenthal GmbH (DE) | 2004-08-11 | — | — | EP | claimed |
| WO-2003037879-A1 | SUBSTITUTED (1H)-QUINOXALIN-2-ONE COMPOUNDS AND SUBSTITUTED 4-ARYL- AND 4-HETEROARYLCYCLOHEXANE COMPOUNDS | Grünenthal GmbH (DE) | 2003-05-08 | — | — | WO | claimed |
| CN-118851895-A | Method for continuously synthesizing 4-acetylcyclohexylbenzene by using microchannel reactor | 品恩赢创(苏州)新材料科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118851895-A | Method for continuously synthesizing 4-acetylcyclohexylbenzene by using microchannel reactor | 品恩赢创(苏州)新材料科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118851895-A | Method for continuously synthesizing 4-acetylcyclohexylbenzene by using microchannel reactor | 品恩赢创(苏州)新材料科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| US-11034725-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| CN-112341320-A | Novel synthesis method of p- (trans-4-hydroxycyclohexyl) phenol | 烟台丰鲁精细化工有限责任公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112341320-A | Novel synthesis method of p- (trans-4-hydroxycyclohexyl) phenol | 烟台丰鲁精细化工有限责任公司 | 2021-02-09 | — | — | CN | disclosed |
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | GENENTECH, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| CN-1022490-C | Liquid crystal mixture | BROTSKEY MILITARY TECHNOLOGY A (PL) | 1993-10-20 | — | — | CN | disclosed |
| CN-87101284-A | Preparation of liquid crystalline cyclohexylbenzene derivatives and novel nematic mixtures containing them | BROTSKEY MILITARY TECHNOLOGY A (PL) | 1988-12-14 | — | — | CN | disclosed |
| EP-0272580-A2 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1988-06-29 | — | — | EP | disclosed |
| EP-0102047-B1 | 1-(TRANS-4-ALKYLCYCLOHEXYL)-2-(TRANS-4'-(P-SUBSTITUTED PHENYL)CYCLOHEXYL)ETHANE AND LIQUID CRYSTAL MIXTURE | ASAHI GLASS COMPANY LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4514044-A | 1-(Trans-4-alkylcyclohexyl)-2-(trans-4'-(p-substituted phenyl) cyclohexyl)ethane and liquid crystal mixture | ASAHI GLASS COMPANY LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| EP-0102047-A1 | 1-(Trans-4-alkylcyclohexyl)-2-(trans-4'-(p-substituted phenyl)cyclohexyl)ethane and liquid crystal mixture | ASAHI GLASS COMPANY LTD. (JP) | 1984-03-07 | — | — | EP | disclosed |
| US-4237026-A | Liquid crystalline carboxylic acid esters | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-02 | — | — | US | disclosed |
| EP-0012820-A1 | Liquid crystalline carboxylic acid esters, process for their preparation, dielectrics containing them and electro-optical display device | MERCK PATENT GmbH (DE) | 1980-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11034725-B2 | Compositions and methods for treating cardiovascular disease | PCSK9, PCSK7, PCSK6 | AKR1C3 824/4885AKR1C1 1393/4885NPC1 161/4885 |
| US-10787484-B2 | Compositions and methods for treating cardiovascular disease | PCSK9, PCSK7, PCSK6 | AKR1C3 824/4885AKR1C1 1393/4885NPC1 161/4885 |
| US-20040224954-A1 | Substituted 1H-quinoxalin-2-one compounds and substituted 4-aryl- and 4-heteroarylcyclohexane compounds | NQO2, NQO1, CYP2C8 | AKR1C3 1047/4885AKR1C1 1102/4885NPC1 1444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.