Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19868903 | 0.83 | AKR1C3 (0.61) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL1836974 | 0.83 | AKR1C3 (0.61) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL2448396 | 0.83 | AKR1C3 (0.61) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL3516198 | 0.79 | NPC1 (0.79) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL2511695 | 0.79 | NPC1 (0.79) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL664284 | 0.79 | NPC1 (0.79) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL11099195 | 0.79 | AKR1C3 (0.66) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| Methacrylic Acid SCHEMBL28100513 | 0.79 | KMO (0.51) | AKR1C3AKR1C1SLC18A3SIGMAR1KDM4E | |
| Bicarbonate SCHEMBL1720488 | 0.78 | AKR1C3 (0.63) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| Bicarbonate SCHEMBL7573346 | 0.78 | AKR1C3 (0.63) | AKR1C3AKR1C1NPC1RAB9ADEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110129622-A1 | ALIGNMENT LAYER FOR LCD | LACHEZAR KOMITOV (SE) | 2011-06-02 | — | — | US | disclosed |
| WO-2009156483-A1 | ALIGNMENT LAYER FOR LCD | KOMITOV LACHEZAR (SE) | 2009-12-30 | — | — | WO | disclosed |