Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.79 |
| ▸ | RAB9A | P51151 | 1/20 | 0.79 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.78 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.78 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3516198 | 1.00 | NPC1 (0.79) | NPC1RAB9AAKR1C3AKR1C1DEGS1 | |
| SCHEMBL2511695 | 1.00 | NPC1 (0.79) | NPC1RAB9AAKR1C3AKR1C1DEGS1 | |
| Hydrochloric Acid SCHEMBL10892943 | 0.98 | NPC1 (0.76) | NPC1RAB9AAKR1C3AKR1C1DEGS1 | |
| SCHEMBL4444928 | 0.98 | NPC1 (0.76) | NPC1RAB9AAKR1C3AKR1C1DEGS1 | |
| SCHEMBL4449225 | 0.98 | NPC1 (0.76) | NPC1RAB9AAKR1C3AKR1C1DEGS1 | |
| SCHEMBL27478716 | 0.98 | NPC1 (0.76) | NPC1RAB9AAKR1C3AKR1C1DEGS1 | |
| SCHEMBL3278764 | 0.88 | NPC1 (1.00) | NPC1RAB9AAKR1C3AKR1C1DEGS1 | |
| SCHEMBL1073107 | 0.88 | AKR1C3 (1.00) | NPC1RAB9AAKR1C3AKR1C1DEGS1 | |
| SCHEMBL26144401 | 0.88 | AKR1C3 (1.00) | NPC1RAB9AAKR1C3AKR1C1DEGS1 | |
| SCHEMBL17811172 | 0.88 | AKR1C3 (1.00) | NPC1RAB9AAKR1C3AKR1C1DEGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688124-B1 | ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2023-10-25 | — | — | EP | claimed |
| CN-116082289-A | 4-R-phenylcyclohexyl formaldehyde ethylene glycol and preparation method thereof | 河北凡克新材料有限公司 | 2023-05-09 | — | — | CN | claimed |
| EP-2185007-B1 | MONO- OR BICYCLIC CARBOXYLIC ACIDS AS OFF-NOTE BLOCKERS | GIVAUDAN SA (CH) | 2018-05-23 | — | — | EP | claimed |
| US-20160205978-A1 | MONO- OR BICYCLIC CARBOXYLIC ACIDS AS OFF-NOTE BLOCKERS | GIVAUDAN SA (CH) | 2016-07-21 | — | — | US | claimed |
| US-20100311786-A1 | MONO- OR BICYCLIC CARBOXYLIC ACIDS AS OFF-NOTE BLOCKERS | GIVAUDAN SA (CH) | 2010-12-09 | — | — | US | claimed |
| EP-2185007-A2 | MONO- OR BICYCLIC CARBOXYLIC ACIDS AS OFF-NOTE BLOCKERS | Givaudan SA (CH) | 2010-05-19 | — | — | EP | claimed |
| WO-2009015504-A2 | MONO- OR BICYCLIC CARBOXYLIC ACIDS AS OFF-NOTE BLOCKERS | GIVAUDAN SA (CH) | 2009-02-05 | — | — | WO | claimed |
| EP-1171511-B1 | A PROCESS FOR PRODUCING POLY(ARYLENE SULFIDE) | CONOCOPHILLIPS CO (US) | 2006-04-19 | — | — | EP | claimed |
| US-5179193-A | From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-12 | — | — | US | claimed |
| US-5177174-A | Branched aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-05 | — | — | US | claimed |
| JP-1075445-A | — | — | None | — | — | JP | disclosed |
| CN-122029148-A | N-phenyl-3- (2, 5-dioxopyrrolidin-1-yl) propionamide derivatives and similar compounds as DUX4 inhibitors for the treatment of, for example, neuromuscular diseases | 阿勒泰治疗公司 | 2026-05-12 | — | — | CN | disclosed |
| US-12162871-B2 | Inhibitors of VAP-1 | ACUCELA INC. (US) | 2024-12-10 | — | — | US | disclosed |
| EP-3688124-B1 | ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2023-10-25 | — | — | EP | disclosed |
| US-11787791-B2 | Inhibitors of VAP-1 | ACUCELA INC. (US) | 2023-10-17 | — | — | US | disclosed |
| JP-S6475445-A | PRODUCTION OF 4'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID | MITSUI TOATSU CHEMICALS | 1989-03-22 | — | — | JP | disclosed |
| EP-0272580-A2 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1988-06-29 | — | — | EP | disclosed |
| EP-0233267-A1 | SMECTIC CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1987-08-26 | — | — | EP | disclosed |
| WO-1987001717-A2 | SMECTIC CYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-03-26 | — | — | WO | disclosed |
| US-4109015-A | PROSTAGLANDINS, LUTEOLYTIC | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787791-B2 | Inhibitors of VAP-1 | VAPB, VAPA, TOE1 | NPC1 198/4885RAB9A 829/4885AKR1C3 4526/4885 |
| US-20100311786-A1 | MONO- OR BICYCLIC CARBOXYLIC ACIDS AS OFF-NOTE BLOCKERS | SORD, GLUL, ASNS | NPC1 2443/4885RAB9A 2876/4885AKR1C3 1058/4885 |
| US-12162871-B2 | Inhibitors of VAP-1 | VAPB, VAPA, TOE1 | NPC1 198/4885RAB9A 829/4885AKR1C3 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.