Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.31 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24470059 | 0.94 | P2RX7 (0.32) | TSHRNR1H2NR1H3P2RX7 | |
| SCHEMBL24484050 | 0.89 | — | — | |
| SCHEMBL24469799 | 0.89 | P2RX7 (0.34) | TSHRRAB9ANR1H2NR1H3P2RX7 | |
| SCHEMBL24484702 | 0.89 | — | — | |
| SCHEMBL26841996 | 0.86 | P2RX7 (0.33) | NR1H2NR1H3P2RX7 | |
| SCHEMBL24483821 | 0.83 | SCD (0.34) | NR1H2NR1H3P2RX7 | |
| SCHEMBL24484039 | 0.82 | MTHFD2 (0.30) | — | |
| SCHEMBL24469803 | 0.81 | NR1H2 (0.32) | NR1H2NR1H3P2RX7 | |
| SCHEMBL26841980 | 0.81 | NR1H2 (0.33) | NR1H2NR1H3P2RX7 | |
| SCHEMBL26841995 | 0.81 | NR1H2 (0.33) | NR1H2NR1H3P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115384-A1 | TRICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2022-06-02 | — | — | WO | disclosed |